Results 311 to 320 of about 54,606 (348)

Epoxidation of chalcones

Chemistry of Heterocyclic Compounds, 1971
Previously undescribed aromatic α-keto oxides have been obtained by the epoxidation of chalcones with alkaline hydrogen peroxide in methanolic solution.
V. F. Belyaev, N. M. Yatsevich
openaire   +2 more sources

Targeting STAT3 and NF-κB Signaling Pathways in Cancer Prevention and Treatment: The Role of Chalcones

Cancers
Simple Summary Chalcones are natural compounds with proven biological properties, including anticancer activities. However, their low bioavailability encourages the design of new synthetic derivatives whose modified structure would increase the ...
V. Krajka-Kuźniak, Marta Belka, Katarzyna Papierska   +2 more
semanticscholar   +1 more source

Direct antibacterial and antibiotic resistance modulatory activity of chalcones synthesized from the natural product 2-hydroxy-3,4,6-trimethoxyacetophenone.

FEMS Microbiology Letters, 2020
Antibiotic for clinical use lose its effectiveness over time due to bacterial resistance. In this work, four chalcones with modifications in their ligands were synthesized from the natural product 2-hydroxy-3,4,6-trimethoxyacetophenone, characterized by ...
T. S. Freitas, J. C. Xavier, R. L. Pereira, J. Rocha, Dédora F Muniz, P. T. da Silva, João P da Hora, Hélcio S dos Santos, P. Bandeira, C. Nogueira, A. Teixeira, H. Coutinho   +11 more
semanticscholar   +1 more source

Chemical sensing of chalcones by voltammetry: trans-Chalcone, cardamonin and xanthohumol

Electrochimica Acta, 2013
Abstract Xanthohumol (XN) and cardamonin (CD) belong to the chemical class of chalcones which are phenolic compounds of large interest due to their health promoting properties. In the present work, their electrochemical behavior on a hanging mercury drop electrode (HMDE) is compared to trans -chalcone by means of cyclic voltammetry (CV).
Tavares, E.M., Carvalho, A.M., Gonçalves, Luis M., Valente, I.M., Moreira, M.M., Guido, L.F., Rodrigues, J.A., Doneux, Thomas, Barros, Aquiles   +8 more
openaire   +2 more sources

An Amine‐Promoted Aziridination of Chalcones.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mei-Xin Zhao, Jiaxi Xu, Yu-Mei Shen, Yian Shi   +3 more
openaire   +4 more sources

Chalcones: As potent α-amylase enzyme inhibitors; synthesis, in vitro, and in silico studies.

Medicinal chemistry, 2020
BACKGROUND The inhibition of α-amylase enzyme is one of the best therapeutic approach for the management of type II diabetes mellitus. Chalcone possesses a wide range of biological activities.
Mahboob Ali, Momin Khan, K. Zaman, A. Wadood, M. Iqbal, A. Alam, Sana Shah, A. Rehman, M. Yousaf, R. Rafique, K. Khan   +10 more
semanticscholar   +1 more source

Polarographic reduction of chalcones [PDF]

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1972
1. The influence of substituents on the polarographic reduction of chalcones and their vinylogs is exerted chiefly according to an inductive mechanism, and as a result of this decreased rapidly with increasing length of the chain of double bonds. 2.
V. F. Kucherov, B. Umirzakov, L. A. Yanovskaya   +2 more
openaire   +1 more source

Recent developments in biological aspects of chalcones: the odyssey continues

Expert Opinion on Drug Discovery, 2019
Introduction: Chalcones are attractive to synthetic chemists because they are easy to prepare, have a large number of replaceable hydrogens, thereby having significant biological potential.
A. Rani, A. Anand, Kewal Kumar, Vipan Kumar   +3 more
semanticscholar   +1 more source

Anticancer Active Heterocyclic Chalcones: Recent Developments.

Anti-Cancer Agents in Medicinal Chemistry, 2020
BACKGROUND Chalcones are structurally simple compounds that are easily accessible by synthetic methods. Heterocyclic chalcones have gained the interest among scientists due to their diverse biological activities. The anti-tumor activities of heterocyclic
P. Dandawate, K. Ahmed, S. Padhye, Aamir Ahmad, B. Biersack   +4 more
semanticscholar   +1 more source

Coupling–Isomerization Synthesis of Chalcones

Chemistry – A European Journal, 2006
AbstractThe Sonogashira coupling of electron‐deficient (hetero)aryl halides 1 and (hetero)aryl or alkenyl 1‐propargyl alcohols 2 does not terminate at the stage of the expected internal propargyl alcohols, but rather gives rise to the formation of α,β‐unsaturated ketones 3 with a variety of acceptor substituents.
Thomas Müller, Roland U. Braun, Markus Ansorge   +2 more
openaire   +4 more sources