Results 81 to 90 of about 25,157 (251)

The Plant-Derived Chalcone 2,2',5'-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia [PDF]

open access: yes, 2016
Chalcones are plant metabolites with potential for therapeutic exploitation as antioxidant, anti-inflammatory, and antiproliferative agents. Here we explored the neuroprotective effects of 2,2',5'-trihydroxychalcone (225THC), a potent antioxidant with ...
Butler, M   +4 more
core   +2 more sources

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek   +3 more
wiley   +1 more source

Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives

open access: yesE-Journal of Chemistry, 2009
2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5 ...
CH. Sridevi   +3 more
doaj   +1 more source

Ultrasound Assisted Synthesis of Chalcones as Green Corrosion Inhibitors for Mild Steel in 1M Hydrochloric Solution

open access: yesInternational Journal of Electrochemical Science, 2014
The three chalcones namely (E)-3-(4-hydroxyphenyl)-N-phenylacrylamide (INH-1), (E)-3- (4dimethylamino)phenyl)-N-phenylacrylamide (INH-2) and (E) -3-(4-hydroxy-3-methoxyphenyl)-N- phenylacrylamide (INH-3) were synthesized and their corrosion inhibition ...
Pooja Singh   +3 more
doaj   +1 more source

Antimicrobial, Antioxidant, and Anticancer Activities of Some Novel Isoxazole Ring Containing Chalcone and Dihydropyrazole Derivatives

open access: yesMolecules, 2020
Our previous work identified isoxazole-based chalcones and their dihydropyrazole derivatives as two important five-membered heterocycles having antitubercular activity.
Afzal Shaik   +5 more
doaj   +1 more source

Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]

open access: yes, 2019
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone   +8 more
core   +2 more sources

University teaching of mass spectrometry as a key practical technique within the context of a fully integrated, spiral curriculum

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall   +3 more
wiley   +1 more source

Synthesis, Antioxidant and Antimicrobial Activities of a Novel Series of Chalcones, Pyrazolic Chalcones, and Allylic Chalcones

open access: yesPharmacology & Pharmacy, 2011
A new series of chalcones (4a-c) and allylicchalcones (11a-b) have been prepared by the Claisen-Schmidt condensation. A novel series of pyrazolicchalcones (5a-c) have been synthesized by the reaction of respective chalcones (4a-c) and hydrazine hydrate.
Tan Nhut Doan, Dao Thanh Tran
openaire   +2 more sources

Synthesis and characterization of phosphine substituted organometallic chalcones [PDF]

open access: yes, 2014
The current focus in organometallic chalcones is based upon their synthesis, eloectrochemical properties, diverse biological behavior and their facet towards a new field “bioorganometallics’’ concerning both organometallic and coordination chemistry ...
Betal, J
core  

Stereoselective photodimerisation of chalcones in the molten state [PDF]

open access: yes, 1998
Photodimerisations of chalcone and its derivatives in the molten state proceed efficiently and stereoselectively to give rac-anti-head-to-head dimers in all cases ...
Kato Masako   +5 more
core   +2 more sources

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