Results 81 to 90 of about 25,157 (251)
The Plant-Derived Chalcone 2,2',5'-Trihydroxychalcone Provides Neuroprotection against Toll-Like Receptor 4 Triggered Inflammation in Microglia [PDF]
Chalcones are plant metabolites with potential for therapeutic exploitation as antioxidant, anti-inflammatory, and antiproliferative agents. Here we explored the neuroprotective effects of 2,2',5'-trihydroxychalcone (225THC), a potent antioxidant with ...
Butler, M +4 more
core +2 more sources
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek +3 more
wiley +1 more source
Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5 ...
CH. Sridevi +3 more
doaj +1 more source
The three chalcones namely (E)-3-(4-hydroxyphenyl)-N-phenylacrylamide (INH-1), (E)-3- (4dimethylamino)phenyl)-N-phenylacrylamide (INH-2) and (E) -3-(4-hydroxy-3-methoxyphenyl)-N- phenylacrylamide (INH-3) were synthesized and their corrosion inhibition ...
Pooja Singh +3 more
doaj +1 more source
Our previous work identified isoxazole-based chalcones and their dihydropyrazole derivatives as two important five-membered heterocycles having antitubercular activity.
Afzal Shaik +5 more
doaj +1 more source
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone +8 more
core +2 more sources
Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall +3 more
wiley +1 more source
A new series of chalcones (4a-c) and allylicchalcones (11a-b) have been prepared by the Claisen-Schmidt condensation. A novel series of pyrazolicchalcones (5a-c) have been synthesized by the reaction of respective chalcones (4a-c) and hydrazine hydrate.
Tan Nhut Doan, Dao Thanh Tran
openaire +2 more sources
Synthesis and characterization of phosphine substituted organometallic chalcones [PDF]
The current focus in organometallic chalcones is based upon their synthesis, eloectrochemical properties, diverse biological behavior and their facet towards a new field “bioorganometallics’’ concerning both organometallic and coordination chemistry ...
Betal, J
core
Stereoselective photodimerisation of chalcones in the molten state [PDF]
Photodimerisations of chalcone and its derivatives in the molten state proceed efficiently and stereoselectively to give rac-anti-head-to-head dimers in all cases ...
Kato Masako +5 more
core +2 more sources

