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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Choosing Challenges in Challenge-Based Courses
Teaching & Learning ...
Bohm, Nina +3 more
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Editor: Ida Rousseau Mukenge, Department of Sociology, Morehouse College Managing Editor: Dr. Obie Clayton, Jr. Editorial Assistant: lretha Johnson Stoney, Morehouse Research Institute Editorial Board Delores P.
Mukenge, Ida Rousseau
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Editor: Ida Rousseau Mukenge, Department of Sociology, Morehouse College Editorial Assistant: Iretba Johnson Stoney Editorial Board Delores P.
Mukenge, Ida Rousseau
core
Editor: Ida Rousseau Mukenge, Department of Sociology, Morehouse College.
Mukenge, Ida Rousseau
core +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Editor: Ida Rousseau Mukenge, Department of Sociology, Morehouse College Editorial Assistant: lretha Johnson Stoney Editorial Board Delores P. Aldridge, Emory University Gloria Lindsey Alibaruho, Diversity, Design, Development Consultants Walter R. Allen,
Mukenge, Ida Rousseau
core

