Results 81 to 90 of about 3,527,028 (317)

Challenge, Vol. 6, Issue 1

, 2019
This issue of Challenge commemorates the 100th anniversary of the birth of Benjamin E.
Carter, Lawrence Edward, Clayton, Obie
core  

Understanding what citizens think about Antimicrobial Resistance: Deliberative Polling® in six middle-income countries [version 1; peer review: 2 approved, 1 approved with reservations]

Wellcome Open Research
Background The pandemic of antimicrobial resistance (AMR) will only be mitigated by policy action and innovation and importantly, supported by local and community action. Last year (2024) with the United Nations General Assembly high level meeting on AMR
Marc Mendelson, Louise Gough, Alice Siu, James Fishkin, Hamish Morrow, Sally Davies   +5 more
doaj   +1 more source

Intensive phase treatment outcome and associated factors among patients treated for multi drug resistant tuberculosis in Ethiopia: a retrospective cohort study

BMC Infectious Diseases, 2019
Background Multi-drug resistant Tuberculosis (MDR-TB) is a strain of Mycobacterium tuberculosis that is resistant to at least Rifampicin and Isoniazid drugs. The treatment success rate for MDR-TB cases is lower than for drug susceptible TB. Globally only
Teklu Molie, Zelalem Teklemariam, Eveline Klinkenberg, Yadeta Dessie, Andargachew Kumsa, Hussen Mohammed, Adisalem Debebe, Dawit Assefa, Abebe Habte, Ahmed Bedru, Daniel Fiseha, Berhanu Seyoum   +11 more
doaj   +1 more source

Challenges for education [PDF]

Frontiers in Neurology, 2010
The topic of education has been incorporated into most mission statements at academic institutions, organizations and professional societies, in fact it would be difficult to identify one in which it was absent. Yet, what does it mean, how do we achieve it and is it really viewed as an equal partner in the tripartite mission of clinical care, research,
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

2017 Sustainable LA Grand Challenge Research Symposium Program [PDF]

, 2017
On May 17, 2017, Sustainable LA Grand Challenge (SLA GC) hosted their first symposium showcasing cutting-edge research toward the goal of 100% renewable energy, 100% locally sourced water, and enhanced ecosystem and human health in Los Angeles County by ...
Sustainable LA Grand Challenge
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Utilising a Clinical Metabolomics LC-MS Study to Determine the Integrity of Biological Samples for Statistical Modelling after Long Term −80 °C Storage: A TOFI_Asia Sub-Study

Metabolites
Biological samples of lipids and metabolites degrade after extensive years in −80 °C storage. We aimed to determine if associated multivariate models are also impacted.
Aidan Joblin-Mills, Zhanxuan E. Wu, Ivana R. Sequeira-Bisson, Jennifer L. Miles-Chan, Sally D. Poppitt, Karl Fraser   +5 more
doaj   +1 more source

Sublingual house dust mite immunotherapy has no impact on decrease of circulating erythrocytes upon airway allergen challenge in allergic rhinitis

Scientific Reports, 2017
House dust mite (HDM) allergy is a predominant cause for perennial allergic rhinitis (AR) in Europe. We recently reported that circulating erythrocyte numbers decrease after airway allergen challenge in a murine asthma model and in grass-pollen ...
Galateja Jordakieva, Michael Kundi, Patrick Lemell, René Zieglmayer, Petra Zieglmayer, Jasminka Godnic-Cvar, Erika Jensen-Jarolim   +6 more
doaj   +1 more source

A challenge to Goliath [PDF]

Journal of Cell Biology, 2009
Megapublishers obligate librarians to buy hundreds of journals they do not need in order to access the journals their constituents actually read. The time has come to challenge this business model, which is unsustainable for the libraries.
openaire   +6 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source