Results 91 to 100 of about 4,322,380 (297)

Impact of The Challenge Initiative on Public-Sector Family Planning Service Provision in Pakistan: Evidence from a Difference-in-Differences Analysis

open access: yesOpen Access Journal of Contraception
Ghazunfer Abbas,1 Junaid-ur-Rehman Siddiqui,1 Bushra Rahim Butt,1 Farrukh Amin,2 Sarosh Seemab,1 Shah Faisal Zahir Deraj,3 Waqar Mehmood Memon,4 Akbar Abbas Bangash,1 Amir Saeed,1 Muhammad Aslam Bajwa,1 Zafar Ali Dehraj,1 Aaliya Habib,1 Syed Azizur Rab,1
Abbas G   +14 more
doaj  

A challenge to Goliath [PDF]

open access: yesJournal of Cell Biology, 2009
Megapublishers obligate librarians to buy hundreds of journals they do not need in order to access the journals their constituents actually read. The time has come to challenge this business model, which is unsustainable for the libraries.
openaire   +6 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Challenge of Global Challenges [PDF]

open access: yesGlobal Challenges, 2018
Jörn Ritterbusch   +5 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Understanding what citizens think about Antimicrobial Resistance: Deliberative Polling® in six middle-income countries [version 2; peer review: 2 approved, 3 approved with reservations]

open access: yesWellcome Open Research
Background The pandemic of antimicrobial resistance (AMR) will only be mitigated by policy action and innovation and importantly, supported by local and community action.
Marc Mendelson   +5 more
doaj   +1 more source

Prevalence of tuberculosis among mentally ill patients in conflict-stricken Afghanistan: A cross-sectional study

open access: yesInternational Journal of Infectious Diseases, 2019
Objectives: Tuberculosis (TB) and mental illness share underlying factors such as poverty, malnutrition, and stress. This study’s objective was to determine the prevalence of TB among mentally ill patients in Afghanistan. Methods: A cross-sectional study
G. Qader   +9 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Challenge

open access: yes, 1991
BACKGROUND INFORMATION The Morehouse Research Institute (MRI), established in 1990, promotes an interdisciplinary program of scholarship. It is designed to generate, disseminate, and exchange information which can guide public policy and programs ...
Mukenge, Ida Rousseau
core   +1 more source

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