Results 71 to 80 of about 21,838,293 (340)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Boundary Layer Modelling of Flow Acceleration and Energy Transfer Effects in Smart Pavement Design

Science, Engineering and Technology
The integration of remote technology into the construction industry has advanced the emergence of smart, self-learning infrastructure across all levels of land transportation design and development. However, energy harvesting capabilities for smart road
Festus Fameso, Julius Ndambuki, Williams Kupolati, Jacques Snyman   +3 more
doaj   +1 more source

A change management perspective on public sector cutback management: towards a framework for analysis

, 2017
The financial crisis forces public managers to implement cutbacks within their organization. We argue that adopting a change management perspective contributes to our understanding of cutback management by adding a focus on managerial behaviour regarding
Eduard Schmidt, S. Groeneveld, S. Van de Walle   +2 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Uncovering hub genes and screening of natural CDK1 inhibitors for targeting in hepatocellular carcinoma

In Silico Research in Biomedicine
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, necessitating the identification of novel therapeutic targets. In this study, we utilized microarray-based genomic analysis to identify key up regulated genes in HCC ...
Yashvi Patel, Nandan Dixit, Saumya K. Patel   +2 more
doaj   +1 more source

The Finnish Allergy Program 2008-2018: Society-wide proactive program for change of management to mitigate allergy burden [PDF]

, 2021
Tari Haahtela, Erkka Valovirta, Kimmo Saarinen, Juha Jantunen, Irmeli Lindström, Paula Kauppi, Tiina Laatikainen, Anna S. Pelkonen, Alexander Salava, Erja Tommila, Jean Bousquet, Tuula Vasankari, Mika J. Mäkelä, Tari Haahtela, Mika J. Mäkelä, Krista Abdulla Hama Salih, Péter Csonka, Matti Hannuksela, Paula Hellemaa, Leena von Hertzen, Juha Jantunen, Paula Kauppi, Tuula Ketola, Tiina Laatikainen, Irmli Lindström, Miika Linna, Soili Mäkinen‐Kiljunen, Anna S. Pelkonen, Leena Petman, Mervi Puolanne, Ilkka Repo, Kimmo Saarinen, Alexander Salava, J. Savolainen, Erja Tommila, Erkka Valovirta, Tuula Vasankari   +36 more
openalex   +1 more source

The mediating role of organizational culture: Transformational leadership and change management in virtual teams

Asia Pacific Management Review, 2022
Simranjeet Kaur Bagga, Shikha Gera, S. N. Haque   +2 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Heat Alert and Response Systems in Urban and Rural Communities in Canada

Change and Adaptation in Socio-Ecological Systems, 2014
Health Canada reviewed national and international literature to develop a framework that identifies best practices for developing and implementing Heat Alert and Response Systems (HARS) to protect citizens from extreme heat events.
Berry Peter, Yusa Anna, Morris-Oswald Toni, Rogaeva Anastasia   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source