Results 221 to 230 of about 2,441,926 (254)

Discovery of edodine, a natural compound from Lentinula edodes with antibacterial activity for the biological control of fire blight pathogen Erwinia amylovora

Pest Management Science, EarlyView.
Novel edodine was identified from Lentinula edodes HK761, exhibiting biocontrol potential against fire blight by affecting motility, intracellular ATP level, and cell division of Erwinia amylovora. Abstract BACKGROUND In the search for biological resources with antibacterial activity against Erwinia amylovora, the culture filtrate of Lentinula edodes ...
Yeong Seok Kim, Jae Woo Han, Bomin Kim, Chunggeon Lee, Daeui Park, Jaehyuk Choi, Gyung Ja Choi, Hun Kim   +7 more
wiley   +1 more source

Impact of migalastat therapy on corneal deposits in a female with Fabry disease: A case report. [PDF]

Mol Genet Metab Rep
Vitturi N, Gugelmo G, Zanini F, Carraro G, Lenzini L, Leonardi A.   +5 more
europepmc   +1 more source

Salvianolic Acid C Protects Against Hepatic Ischemia–Reperfusion Injury via Heat Shock Protein 90α‐Mediated Activation of the Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling Pathway

Phytotherapy Research, EarlyView.
Salvianolic acid C (SaC) protects against hepatic ischemia–reperfusion injury (HIRI) by upregulating HSP90α and activating the PI3K/AKT pathway, thereby alleviating oxidative stress, inflammation, apoptosis, and necrosis. ABSTRACT Hepatic ischemia–reperfusion injury (HIRI) is a major challenge in liver surgery, and effective pharmacological ...
Pingping Qiao, Alimu Tulahong, Xinlu Xu, Tiemin Jiang, Ruiqing Zhang, Yanze Lin, Zhongdian Yuan, Rexiati Ruze, Yingmei Shao   +8 more
wiley   +1 more source

Targeting HSP90 in cancer: advances in the development of inhibitors, mechanisms of action, and therapeutic applications. [PDF]

Mol Cancer
Wang X, Ni R, Wang X, Li X.
europepmc   +1 more source

Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights

Smart Molecules, EarlyView.
Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan, Xiaoyu Shi, Qian Yang, Xiangyi Jiang, Xinyong Liu, Peng Zhan   +5 more
wiley   +1 more source

Phase separation in neurodegenerative disorders: a metabolic perspective on protein aggregation and therapeutic targeting. [PDF]

Transl Neurodegener
Peng S, Chen H, Yin G, Verkhratsky A, Yi C.   +4 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

The <i>Drosophila l(3)tb</i> mutant as a model to study stress-inducible Hsp70-expressing brain tumor. [PDF]

MicroPubl Biol
Biswas A, Sinha D.
europepmc   +1 more source

En face localization of retinal telangiectatic capillaries using OCT compared with ICG angiography in chronic vascular macular oedema

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinal telangiectatic capillaries (TelCaps) are microvascular abnormalities associated with chronic vascular macular oedema and suboptimal response to intravitreal therapy. Targeted laser photocoagulation is beneficial but requires precise localization using indocyanine green angiography (ICG‐A), the reference standard. However, ICG‐A
Lucas Unger, Bénédicte Dupas, Mohamed Bennani, Daniela Castro Farias, Jean‐François Girmens, Aude Couturier, Michel Paques, Marie‐Noëlle Delyfer   +7 more
wiley   +1 more source

Cellular Stress and Immune Activation in Celiac Disease: Is the Chaperone System a Key Player? [PDF]

Biology (Basel)
Vergilio G, Vultaggio G, Gagliardo R, Paladino L, Rappa F.   +4 more
europepmc   +1 more source