Results 61 to 70 of about 2,441,926 (254)

Different effects of single and fractionated light delivery regimes in photodynamic therapy with hypericin on HT-29 cells in vitro [PDF]

, 2009
Photodynamic therapy (PDT) is an alternative cancer cure which involves the selective uptake and retention of a photosensitizer in a cancer tissue, followed by irradiation with light of a specific wavelength to kill tumour cells via the production of ...
Grada Kulikova, Lucia
core   +1 more source

Crystal structure of the P pilus rod subunit PapA [PDF]

, 2007
P pili are important adhesive fibres involved in kidney infection by uropathogenic Escherichia coli strains. P pili are assembled by the conserved chaperone-usher pathway, which involves the PapD chaperone and the PapC usher.
Bullitt, E, Hultgren, SJ, Hultgren, Scott J, Denis Verger, Waksman, Gabriel, Hultgren, Scott J., Verger, Denis, Esther Bullitt, Scott J Hultgren, Bullitt, Esther, Waksman, G, Verger, D, Gabriel Waksman   +12 more
core   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential

Frontiers in Aging Neuroscience
The maintenance of protein homeostasis is essential for neuronal survival and function; however, it progressively declines with age, predisposing the brain to neurodegenerative diseases.
Noureddine Ben Khalaf
doaj   +1 more source

Other title: What does the Occupational Therapy, Physical Therapy, and Athletic Trainers Board say about telehealth?

, 2020
"Created: 3/16/2020..."--Document properties ...
Ohio Occupational Therapy, Physical Therapy, and Athletic Trainers Board
core  

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Treatment planning study comparing proton therapy, RapidArc and intensity modulated radiation therapy for a synchronous bilateral lung cancer case

, 2014
Purpose: The main purpose of this study is to perform a treatment planning study on a synchronous bilateral non-small cell lung cancer case using three treatment modalities: uniform scanning proton therapy, RapidArc, and intensity modulated radiation ...
Zheng, Yuanshui; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Zhao, Li; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Risalvato, Dina; Department of Medical Dosimetry, ProCure Proton Therapy Center, Oklahoma City, Oklahoma, USA., Vargas, Carlos; Radiation Oncology, Proton Collaborative Group (PCG), Bloomington, Indiana, USA., Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Pokharel, Shyam; Department of Medical Physics, 21st Century Oncology, Fort Myers, Florida, USA., Cersonsky, Nancy; Department of Radiation Oncology, ProCure Proton Therapy Center, Oklahoma City, Oklahoma, USA.   +6 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Structure, Function and Regulation of the Hsp90 Machinery

Biomedical Journal, 2013
Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone which is essential in eukaryotes. It is required for the activation and stabilization of a wide variety of client proteins and many of them are involved in important cellular pathways.
Jing Li, Johannes Buchner
doaj   +1 more source

Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability

, 2020
The E3 ubiquitin-ligase Hakai binds to several tyrosine-phosphorylated Src substrates, including the hallmark of the epithelial-to-mesenchymal transition E-cadherin, and signals for degradation of its specific targets.
Díaz-Díaz, Roca-Lema, Figueroa, Casas-Pais, Colombo, Graña, Concha, Romay   +7 more
core   +1 more source