Results 101 to 110 of about 110,947 (209)

Extracellular chaperones

, 2013
The maintenance of the levels and correct folding state of proteins (proteostasis) is a fundamental prerequisite for life. Life has evolved complex mechanisms to maintain proteostasis and many of these that operate inside cells are now well understood ...
Rebecca Dabbs (20117175), Heath Ecroyd (19583602), Justin Yerbury (20136507), Amy Wyatt (20117166), Mark Wilson (19585432)   +4 more
core  

Evolvability of Chaperonin Substrate Proteins

, 2009
Molecular chaperones ensure that their substrate proteins reach the functional native state, and prevent their aggregation. Recently, an additional function was proposed for molecular chaperones: they serve as buffers (_capacitors_) for evolution by ...
Tobias Maier, Paolo Ribecaa, Luis Serrano, Tobias Maierb, Paolo Ribeca, Emanuele Raineri, Luis Serranob, Emanuele Raineria   +7 more
core   +1 more source

Molecular chaperones and the protein production line

, 1994
The folding of proteins to their active state in the cell, long thought to be a spontaneous process, requires the assistance of other proteins called molecular chaperones.
Lund, Peter A.
core   +1 more source

Enhancing soluble expression and purification of a bispecific scFv antibody in <i>Escherichia coli</i> using chaperones. [PDF]

Res Pharm Sci
Alidousti-Shahraki Z, Amini-Dehkordi A, Esmaeil N, Akbari V.   +3 more
europepmc   +1 more source

T3SS effector and regulator discovery by predicting interacting partners of T3SS chaperones in Pseudomonas aeruginosa. [PDF]

Protein Sci
Zhang J.
europepmc   +1 more source

Escorting mRNAs - the multifunctional and divergent roles of cap-chaperones in post-transcriptional gene expression. [PDF]

J Cell Sci
Embree CM, Borden KLB.
europepmc   +1 more source

Beyond Inhibition: Rebalancing the Hsp90 Chaperone Network as a Therapeutic Strategy for Alzheimer's Disease. [PDF]

Drug Des Devel Ther
Tang Z, Xie H, Xu Y, Zhou Z, Lu F, Wu Q, Liang W, Zhong M, Li S.   +8 more
europepmc   +1 more source

Molecular chaperons: chaperones and chaperonins

, 2007
Proteins must be folded into their correct three-dimensional conformation in order to attain biological function. Conversely, protein aggregation and misfolding are primary contributors to many devastating "conformational" diseases.
Bregier, Cezary, Fabczak, Stanisław, Fabczak, Hanna   +2 more
core  

Heat Shock Proteins in Medically Relevant Fungal Pathogens: From Molecular Chaperones to Virulence Factors and Therapeutic Targets. [PDF]

J Fungi (Basel)
Padró-Villegas L, Mora-Montes HM.
europepmc   +1 more source

Dynamic disorder is crucial for mitochondrial protein import. [PDF]

Protein Sci
Schneider J, Guillerm U, Pereira CS, Schanda P.   +3 more
europepmc   +1 more source