Results 261 to 270 of about 183,487 (307)
Some of the next articles are maybe not open access.
Seminars in Cell & Developmental Biology, 2000
We discuss nuclear chaperones that bind correctly folded protein subunits and mediate molecular interactions, particularly between proteins and nucleic acids. The charge of these chaperones helps to prevent non-specific electrostatic interactions between the components.
A, Philpott, T, Krude, R A, Laskey
openaire +2 more sources
We discuss nuclear chaperones that bind correctly folded protein subunits and mediate molecular interactions, particularly between proteins and nucleic acids. The charge of these chaperones helps to prevent non-specific electrostatic interactions between the components.
A, Philpott, T, Krude, R A, Laskey
openaire +2 more sources
Biogerontology, 2005
That evolution of longevity may depend on alterations in the expression of relatively few regulatory genes has been inferred from the rapid increase in lifespan during evolution of the hominid species (Cutler RG (1979) Mech Ageing Dev 9: 337-354). Also the inherent immortality of the embryonic stem cells implies that replicative senescence (Hayflick L (
openaire +2 more sources
That evolution of longevity may depend on alterations in the expression of relatively few regulatory genes has been inferred from the rapid increase in lifespan during evolution of the hominid species (Cutler RG (1979) Mech Ageing Dev 9: 337-354). Also the inherent immortality of the embryonic stem cells implies that replicative senescence (Hayflick L (
openaire +2 more sources
Molecular Chaperones: Panning for chaperone-binding peptides
Current Biology, 1994Experiments designed to define the substrate-binding preferences of the molecular chaperone BiP show that bound peptides are characterized by a heptameric motif with alternating hydrophobic residues.
openaire +2 more sources
Ageing is a complex yet universal and inevitable degenerative process that results in a decline in the cellular capacity for repair and adaptation to external stresses. Therefore, maintaining the appropriate balance of the cellular proteome is crucial. In addition to the ubiquitin-proteasome and autophagy-lysosomal systems, molecular chaperones play a ...
openaire +2 more sources
openaire +2 more sources
Chaperones directly and efficiently disperse stress-triggered biomolecular condensates
Molecular Cell, 2022Haneul Yoo +2 more
exaly