Results 61 to 70 of about 27,779 (210)

A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]

, 2019
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn, Burgess, Stewart TG, Down, Rachel E, Dunn, Jackie, Marr, Edward J, Nisbet, Alasdair J, Nunn, Francesca G, Prickett, Jessica C, Rombauts, Stephane, Van de Peer, Yves, Van Leeuwen, Thomas, Weaver, Robert J   +11 more
core   +2 more sources

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque, Aymeric Jacquemin, Delphine Girlich, Rémy A. Bonnin, Laurent Dortet   +4 more
wiley   +1 more source

Solution Structure of the Acetylated and Noncleavable Mitochondrial Targeting Signal of Rat Chaperonin 10 [PDF]

Journal of Biological Chemistry, 1995
Chaperonin 10 (Cpn10) is one of only a few mitochondrial matrix proteins synthesized without a cleavable targeting signal. Using a truncated form of Cpn10 and synthetic peptides in mitochondrial import assays, we show that the N-terminal region is both necessary and sufficient for organellar targeting in vitro.
Jarvis, Jack A., Ryan, Michael T., Hoogenraad, Nicholas J., Craik, David J., Hoj, Peter B.   +4 more
openaire   +4 more sources

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production [PDF]

, 2020
In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many
Alberto Vassallo, Andrea Scaloni, Anna Maria Puglia, Emilia Palazzotto, Giovanni Renzone, Giuseppe Gallo, Luigi Botta, Teresa Faddetta   +7 more
core   +2 more sources

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer

BMC Cancer, 2018
Background Heat Shock Proteins (HSPs), a family of genes with key roles in proteostasis, have been extensively associated with cancer behaviour. However, the HSP family is quite large and many of its members have not been investigated in breast cancer ...
Felipe C. M. Zoppino, Martin E. Guerrero-Gimenez, Gisela N. Castro, Daniel R. Ciocca   +3 more
doaj   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro, J. Carballo, M. C. Pasten, C. A. Gallo, E. Albertini, V. Echenique   +5 more
wiley   +1 more source

Chemical synthesis of 10 kDa chaperonin Biological activity suggests chaperonins do not require other molecular chaperones

FEBS Letters, 1991
Molecular chaperones are required for the correct folding and assembly of certain other polypeptides. It is not known whether molecular chaperones themselves require other chaperones to become functional. A 97‐amino acid chaperone, the chaperonin 10 protein was chemically synthesised so that during synthesis and purification there was no contact of the
Mascagni, Paolo, Tonolo, Mirta, Ball, Haydn, Lim, Marguerita, Ellis, R.John, Coates, Anthony   +5 more
openaire   +2 more sources

Genome‐wide analysis of the AP2/ERF gene family in Rheum officinale Baill.: Evolution and expression profiling during plant development, abiotic stresses, and exogenous hormone responses

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract The APETALA2/ethylene‐responsive factor (AP2/ERF) superfamily plays a central role in plant metabolism, stress responses, and hormone signaling. Rheum officinale Baill. is an important traditional medicinal plant whose roots and rhizomes are rich in anthraquinones and other secondary metabolites.
Jing Tang, Gao‐chang Cui, Heng Pan, Hui Lu, Yi‐min Li, Feng Yan, Jing Gao, Liang Peng, Xiao‐chen Hu, Gang Zhang   +9 more
wiley   +1 more source