Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics
Frontiers in Molecular Biosciences, 2018 The 60 kDa heat shock protein (Hsp60) is classically known as a mitochondrial chaperonin protein working together with co-chaperonin 10 kDa heat shock protein (Hsp10).
Qianli Meng +2 more
doaj +1 more source
Potential marker proteins for ozone-induced yield reduction in rice
Advances in Horticultural Science, 2018 Three proteins - a 60-kDa chaperonin (CPN-60), chloroplastic ATP synthase, and enolase 1 - were evaluated as potential markers of ozone-induced yield responses in six rice (Oryza sativa L.) cultivars (‘Kirara 397’, ‘Koshihikari’, ‘Nipponbare’, ‘Takanari’,
H. Sawada +3 more
doaj +1 more source
Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer. [PDF]
PLoS ONE, 2014 Heat shock protein 60 (HSP60) is a chaperonin with essential functions for cell physiology and survival, and its expression correlates with prognosis in a number of malignancies. The aim of this study is to determine the relationship of HSP60 status with
Xiao-shan Li +3 more
doaj +1 more source
GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus
Diagnostics, 2022 A point-of-care diagnostic for early and rapid diagnosis of scrub typhus caused by Orientia tsutsugamushi is required for prompt and proper treatment of patients presenting with undifferentiated febrile illnesses.
Nitaya Indrawattana +7 more
doaj +1 more source
Pb2+ tolerance by Frankia sp. strain EAN1pec involves surface-binding [PDF]
, 2017 Several Frankia strains have been shown to be lead-resistant. The mechanism of lead resistance was investigated for Frankia sp. strain EAN1pec. Analysis of the cultures by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDAX ...
Furnholm, Teal +3 more
core +2 more sources
Expression of plant chaperonin-60 genes in Escherichia coli
Journal of Biological Chemistry, 1992 We have examined the expression in Escherichia coli of genes encoding a plant chloroplast molecular chaperone, chaperonin-60. Purified plant chaperonin-60 is distinct in that it contains two polypeptides, p60cpn-60 alpha and p60cpn-60 beta, which have divergent amino acid sequences (Hemmingsen, S. M., and Ellis, R. J. (1986) Plant Physiol. 80, 269-276;
H B Wu, L P Cloney, Sean M. Hemmingsen
openaire +3 more sources
Mycobacterium tuberculosis expresses two chaperonin-60 homologs. [PDF]
Proceedings of the National Academy of Sciences, 1993 A 65-kDa protein and a 10-kDa protein are two of the more strongly immunoreactive components of Mycobacterium tuberculosis, the causative agent of tuberculosis. The 65-kDa antigen has homology with members of the GroEL or chaperonin-60 (Cpn60) family of heat shock proteins.
T H, Kong +4 more
openaire +2 more sources
Root exudate-induced alterations in Bacillus cereus cell wall contribute to root colonization and plant growth promotion. [PDF]
PLoS ONE, 2013 The outcome of an interaction between plant growth promoting rhizobacteria and plants may depend on the chemical composition of root exudates (REs). We report the colonization of tobacco, and not groundnut, roots by a non-rhizospheric Bacillus cereus ...
Swarnalee Dutta +2 more
doaj +1 more source
The pathogen Moniliophthora perniciosa promotes differential proteomic modulation of cacao genotypes with contrasting resistance to witches´ broom disease [PDF]
, 2020 Background: Witches' broom disease (WBD) of cacao (Theobroma cacao L.), caused by Moniliophthora perniciosa, is the most important limiting factor for the cacao production in Brazil.
Correa, Stephany Cristiane +4 more
core +1 more source
PLoS ONE, 2014 The human Aβ peptide causes progressive paralysis when expressed in the muscles of the nematode worm, C. elegans. We have exploited this model of Aβ toxicity by carrying out an RNAi screen to identify genes whose reduced expression modifies the severity ...
Eleonora Khabirova +8 more
doaj +1 more source