Results 41 to 50 of about 13,221 (182)

B-cell epitopes in GroEL of Francisella tularensis. [PDF]

PLoS ONE, 2014
The chaperonin protein GroEL, also known as heat shock protein 60 (Hsp60), is a prominent antigen in the human and mouse antibody response to the facultative intracellular bacterium Francisella tularensis (Ft), the causative agent of tularemia.
Zhaohua Lu, Michael J Rynkiewicz, Guillermo Madico, Sheng Li, Chiou-Ying Yang, Hillary M Perkins, Seshi R Sompuram, Vani Kodela, Tong Liu, Timothy Morris, Daphne Wang, Marly I Roche, Barbara A Seaton, Jacqueline Sharon   +13 more
doaj   +1 more source

Detection of immunoreactive proteins of Escherichia coli, Streptococcus uberis, and Streptococcus agalactiae isolated from cows with diagnosed mastitis

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionMastitis is a widespread mammary gland disease of dairy cows that causes severe economic losses to dairy farms. Mastitis can be caused by bacteria, fungi, and algae.
Anna Dobrut, Dagmara Wójcik-Grzybek, Agata Młodzińska, Dorota Pietras-Ożga, Katarzyna Michalak, Aleksander Tabacki, Urszula Mroczkowska, Monika Brzychczy-Włoch   +7 more
doaj   +1 more source

Immunochemical localization of a region of chaperonin-60 important for productive interaction with chaperonin-10.

Journal of Biological Chemistry, 1992
An IgG1 monoclonal antibody (mAb 54G8) which binds to both Bordetella pertussis chaperonin-60 (cpn60) and Escherichia coli cpn60 (GroEL) was produced. mAb 54G8 as well as Fab fragments prepared from this antibody were found to abolish the ability of chaperonin-10 (cpn10, GroES) to inhibit the ATPase activity of both B. pertussis cpn60 and E. coli cpn60.
D L, Burns, M, Kessel, J L, Arciniega, A, Karpas, J, Gould-Kostka   +4 more
openaire   +2 more sources

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source

Transcriptomic and proteomic profiles of II YOU 838 (Oryza sativa) provide insights into heat stress tolerance in hybrid rice [PDF]

PeerJ, 2020
Heat stress is an increasing threat to rice production worldwide. To investigate the mechanisms of heat tolerance in hybrid rice and their contributions to rice heterosis, we compared the transcriptome of the hybrid rice II YOU 838 (II8) with the ...
Yan Wang, Yang Yu, Min Huang, Peng Gao, Hao Chen, Mianxue Liu, Qian Chen, Zhirong Yang, Qun Sun   +8 more
doaj   +2 more sources

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Comparative Proteome Analysis of Wheat Flag Leaves and Developing Grains Under Water Deficit

Frontiers in Plant Science, 2018
In this study, we performed the first comparative proteomic analysis of wheat flag leaves and developing grains in response to drought stress. Drought stress caused a significant decrease in several important physiological and biochemical parameters and ...
Xiong Deng, Yue Liu, Xuexin Xu, Dongmiao Liu, Genrui Zhu, Xing Yan, Zhimin Wang, Yueming Yan   +7 more
doaj   +1 more source

Quantitative molecular diagnostic assays of grain washes for Claviceps purpurea are correlated with visual determinations of ergot contamination. [PDF]

PLoS ONE, 2017
We examined the epiphytic microbiome of cereal grain using the universal barcode chaperonin-60 (cpn60). Microbial community profiling of seed washes containing DNA extracts prepared from field-grown cereal grain detected sequences from a fungus ...
Alexia Comte, Tom Gräfenhan, Matthew G Links, Sean M Hemmingsen, Tim J Dumonceaux   +4 more
doaj   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Helicobacter hepaticus is required for immune targeting of bacterial heat shock protein 60 and fatal colitis in mice

Gut Microbes, 2021
Gut microbiota and the immune system are in constant exchange shaping both host immunity and microbial communities. Here, improper immune regulation can cause inflammatory bowel disease (IBD) and colitis. Antibody therapies blocking signaling through the
Verena Friedrich, Ignasi Forné, Dana Matzek, Diana Ring, Bastian Popper, Lara Jochum, Stefanie Spriewald, Tobias Straub, Axel Imhof, Anne Krug, Bärbel Stecher, Thomas Brocker   +11 more
doaj   +1 more source