Redox Biology, 2021 Hydrogen peroxide (H2O2) is widely used in clinical practice due to its antiseptic properties and its ability to heal wounds. However, due to its involvement in the formation of ROS, H2O2 causes several side effects, including disorders of the metabolism
Sinemyiz Atalay +3 more
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Comparative genomic analysis of mollicutes with and without a chaperonin system. [PDF]
PLoS ONE, 2018 The GroE chaperonin system, which comprises GroEL and GroES, assists protein folding in vivo and in vitro. It is conserved in all prokaryotes except in most, but not all, members of the class of mollicutes.
Dominik Schwarz +3 more
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Expression of plant chaperonin-60 genes in Escherichia coli
Journal of Biological Chemistry, 1992 We have examined the expression in Escherichia coli of genes encoding a plant chloroplast molecular chaperone, chaperonin-60. Purified plant chaperonin-60 is distinct in that it contains two polypeptides, p60cpn-60 alpha and p60cpn-60 beta, which have divergent amino acid sequences (Hemmingsen, S. M., and Ellis, R. J. (1986) Plant Physiol. 80, 269-276;
H B Wu, L P Cloney, Sean M. Hemmingsen
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Scientific Reports, 2021 Blueberry stunt phytoplasma (BBSP; ‘Candidatus Phytoplasma asteris’) is an insect-vectored plant pathogen that causes severe yield losses in blueberry (Vaccinium corymbosum), which is the most valuable fruit crop in Canada.
Christine Hammond +5 more
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Capturing the essence of folding and functions of biomolecules using Coarse-Grained Models
, 2011 The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example during chromosome organization. Describing phenomena that cover such diverse length,
A Dhar +89 more
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Optimizing a PCR protocol for cpn60-based microbiome profiling of samples variously contaminated with host genomic DNA. [PDF]
, 2015 The current recommended protocol for chaperonin-60 (cpn60) universal target based microbiome profiling includes universal PCR of microbiome samples across an annealing temperature gradient to maximize the diversity of sequences amplified.
Chaban, B +3 more
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The pathogen Moniliophthora perniciosa promotes differential proteomic modulation of cacao genotypes with contrasting resistance to witches´ broom disease [PDF]
, 2020 Background: Witches' broom disease (WBD) of cacao (Theobroma cacao L.), caused by Moniliophthora perniciosa, is the most important limiting factor for the cacao production in Brazil.
Correa, Stephany Cristiane +4 more
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60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis
European Journal of Histochemistry, 2009 The aim of the present study was to evaluate the expression of the heat shock protein 60 (HSP60), a mitochondrial matrix-associated protein belonging to the chaperonin family, in colorectal adenomas and cancers, comparing them to normal colonic tissues ...
F Cappello +10 more
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Comparative proteomic profiling of human bile reveals SSP411 as a novel biomarker of cholangiocarcinoma. [PDF]
PLoS ONE, 2012 BACKGROUND: Cholangiocarcinoma (CC) is an intractable cancer, arising from biliary epithelial cells, which has a poor prognosis and is increasing in incidence.
Jian Shen +12 more
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Streptococcus suis Serotypes Characterized by Analysis of Chaperonin 60 Gene Sequences [PDF]
Applied and Environmental Microbiology, 2001 ABSTRACT Streptococcus suis is an important pathogen of swine which occasionally infects humans as well. There are 35 serotypes known for this organism, and it would be desirable to develop rapid methods methods to identify and differentiate the strains of this species.
Brousseau, Ronald +5 more
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