Results 51 to 60 of about 24,211 (206)

B-cell epitopes in GroEL of Francisella tularensis. [PDF]

PLoS ONE, 2014
The chaperonin protein GroEL, also known as heat shock protein 60 (Hsp60), is a prominent antigen in the human and mouse antibody response to the facultative intracellular bacterium Francisella tularensis (Ft), the causative agent of tularemia.
Zhaohua Lu, Michael J Rynkiewicz, Guillermo Madico, Sheng Li, Chiou-Ying Yang, Hillary M Perkins, Seshi R Sompuram, Vani Kodela, Tong Liu, Timothy Morris, Daphne Wang, Marly I Roche, Barbara A Seaton, Jacqueline Sharon   +13 more
doaj   +1 more source

Detection of immunoreactive proteins of Escherichia coli, Streptococcus uberis, and Streptococcus agalactiae isolated from cows with diagnosed mastitis

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionMastitis is a widespread mammary gland disease of dairy cows that causes severe economic losses to dairy farms. Mastitis can be caused by bacteria, fungi, and algae.
Anna Dobrut, Dagmara Wójcik-Grzybek, Agata Młodzińska, Dorota Pietras-Ożga, Katarzyna Michalak, Aleksander Tabacki, Urszula Mroczkowska, Monika Brzychczy-Włoch   +7 more
doaj   +1 more source

The refolding of recombinant human liver methylmalonyl-CoA mutase from inclusion bodies produced in Escherichia coli : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1998
Human methylmalonyl-CoA mutase (hMCM) is an adenosylcobalamin-dependent enzyme that catalyses the structural rearrangement of (R)-methylmalonyl-CoA to succinyl-CoA as pan of the catabolism of the branched chain amino acids valine, leucine and isoleucine,
Hayes, Michelle Marie
core  

A yeast two-hybrid screen reveals a strong interaction between the Legionella chaperonin Hsp60 and the host cell small heat shock protein Hsp10 [PDF]

, 2015
L. pneumophila is an intracellular bacterium that replicates inside a membrane-bound vacuole called Legionella-containing vacuole (LCV), where it plentifully liberates its HtpB chaperonin.
Nasrallah, Gheyath K.
core   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Transcriptomic and proteomic profiles of II YOU 838 (Oryza sativa) provide insights into heat stress tolerance in hybrid rice [PDF]

PeerJ, 2020
Heat stress is an increasing threat to rice production worldwide. To investigate the mechanisms of heat tolerance in hybrid rice and their contributions to rice heterosis, we compared the transcriptome of the hybrid rice II YOU 838 (II8) with the ...
Yan Wang, Yang Yu, Min Huang, Peng Gao, Hao Chen, Mianxue Liu, Qian Chen, Zhirong Yang, Qun Sun   +8 more
doaj   +2 more sources

Brassica napus Plastid and Mitochondrial Chaperonin-60 Proteins Contain Multiple Distinct Polypeptides [PDF]

Plant Physiology, 1994
Plastid chaperonin-60 protein was purified to apparent homogeneity from Brassica napus using a novel protocol. The purified protein, which migrated as a single species by nondenaturing polyacrylamide gel electrophoresis, contained four polypeptides: three variants of p60cpn60 alpha and p60cpn60 beta.
Cloney, L. P., Bekkaoui, D. R., Feist, G. L., Lane, W. S., Hemmingsen, S. M.   +4 more
openaire   +2 more sources

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Quantitative molecular diagnostic assays of grain washes for Claviceps purpurea are correlated with visual determinations of ergot contamination. [PDF]

PLoS ONE, 2017
We examined the epiphytic microbiome of cereal grain using the universal barcode chaperonin-60 (cpn60). Microbial community profiling of seed washes containing DNA extracts prepared from field-grown cereal grain detected sequences from a fungus ...
Alexia Comte, Tom Gräfenhan, Matthew G Links, Sean M Hemmingsen, Tim J Dumonceaux   +4 more
doaj   +1 more source

The effect of nucleotides and mitochondrial chaperonin 10 on the structure and chaperone activity of mitochondrial chaperonin 60 [PDF]

European Journal of Biochemistry, 2001
Mitochondrial chaperonins are necessary for the folding of newly imported and stress‐denatured mitochondrial proteins. The goal of this study was to investigate the structure and function of the mammalian mitochondrial chaperonin system. We present evidence that the 60 kDa chaperonin (mt‐cpn60) exists in solution in dynamic equilibrium between monomers,
G, Levy-Rimler, P, Viitanen, C, Weiss, R, Sharkia, A, Greenberg, A, Niv, A, Lustig, Y, Delarea, A, Azem   +8 more
openaire   +2 more sources