Results 71 to 80 of about 8,360 (214)

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro, J. Carballo, M. C. Pasten, C. A. Gallo, E. Albertini, V. Echenique   +5 more
wiley   +1 more source

Natural supramolecular protein assemblies [PDF]

, 2016
Supramolecular protein assemblies are an emerging area within the chemical sciences, which combine the topological structures of the field of supramolecular chemistry and the state-of-the-art chemical biology approaches to unravel the formation and ...
Mecinović, Jasmin, Nolte, Roeland J. M., Pieters, Bas J. G. E., van Eldijk, Mark B.   +3 more
core   +2 more sources

Genome‐wide analysis of the AP2/ERF gene family in Rheum officinale Baill.: Evolution and expression profiling during plant development, abiotic stresses, and exogenous hormone responses

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract The APETALA2/ethylene‐responsive factor (AP2/ERF) superfamily plays a central role in plant metabolism, stress responses, and hormone signaling. Rheum officinale Baill. is an important traditional medicinal plant whose roots and rhizomes are rich in anthraquinones and other secondary metabolites.
Jing Tang, Gao‐chang Cui, Heng Pan, Hui Lu, Yi‐min Li, Feng Yan, Jing Gao, Liang Peng, Xiao‐chen Hu, Gang Zhang   +9 more
wiley   +1 more source

Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]

, 2007
The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria, Boulangé, Alain, Brizard, Jean-Paul, Courtois, Pierrette, Cuny, Gérard, Daulouède, Sylvie, Frutos, Roger, Grébaut, Pascal, Holzmuller, Philippe, Peltier, Jean-Benoît, Vincendeau, Philippe   +10 more
core  

The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccharomyces cerevisiae

Traffic, Volume 27, Issue 2, June 2026.
Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14 exhibits vacuolar fragmentation, enlarged lipid droplets, and metabolic alterations. Ruiz Salas, J. L. (2026) https://BioRender.com/b65g523. ABSTRACT Erv14 is a
Paul Rosas‐Santiago, Jorge Luis Ruiz Salas, Elizabeth Cordoba, Francisco Vera‐López Portillo, Prisciluis Caheri Salas‐Navarrete, Jaime Arturo Pimentel Cabrera, Alfredo Martínez, Nayeli Imelda Roldan Ramírez, Dieter Chavelas Hernández, Andrés Saralegui‐Amaro, Martha Calahorra, Hana Sychrová, Olga Zimmermannová   +12 more
wiley   +1 more source

cpnDB: A Chaperonin Sequence Database [PDF]

Genome Research, 2004
Type I chaperonins are molecular chaperones present in virtually all bacteria, some archaea and the plastids and mitochondria of eukaryotes. Sequences of cpn60 genes, encoding 60-kDa chaperonin protein subunits (CPN60, also known as GroEL or HSP60), are useful for phylogenetic studies and as targets for detection and identification of organisms ...
Hill, Janet, Penny, S. L., Crowell, K. G., Goh, S. H., Hemmingsen, Sean   +4 more
openaire   +2 more sources

Bardet-Biedl Syndrome as a Chaperonopathy: Dissecting the Major Role of Chaperonin-Like BBS Proteins (BBS6-BBS10-BBS12)

Frontiers in Molecular Biosciences, 2017
Bardet-Biedl syndrome (BBS) is a rare genetic disorder that belongs to the group of ciliopathies, defined as diseases caused by defects in cilia structure and/or function. The six diagnostic features considered for this syndrome include retinal dystrophy,
María Álvarez-Satta, María Álvarez-Satta, María Álvarez-Satta, Sheila Castro-Sánchez, Sheila Castro-Sánchez, Sheila Castro-Sánchez, Diana Valverde, Diana Valverde, Diana Valverde   +8 more
doaj   +1 more source

Phosphate Limitation Modulates Vibrio Cholerae Outer Membrane Vesicle Formation, Composition and Toxicity

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Vibrio cholerae inhabits phosphorus‐poor aquatic environments and host intestine, where it expresses genes regulated by the PhoB/PhoR two‐component system in response to inorganic phosphate (Pi) limitation. Like other Gram‐negative bacteria, V.
Matheus Luchetta da Fonseca, Livia Carvalho Barbosa, Beatriz Ferreira de Carvalho Patricio, Wellington da Silva Ferreira, Carolina Neumann Keim, Cedric Delporte, Pierre van Antwerpen, Jean‐Marie Ruysschaert, Paulo Mascarello Bisch, Wanda Maria Almeida von Kruger   +9 more
wiley   +1 more source