Results 81 to 90 of about 5,379 (199)
Directed Evolution of Substrate-Optimized GroEL/S Chaperonins [PDF]
, 2002 GroEL/S chaperonin ring complexes fold many unrelated proteins. To understand the basis and extent of the chaperonin substrate spectrum, we used rounds of selection and DNA shuffling to obtain GroEL/S variants that dramatically enhanced folding of a ...
Gross, Carol A. +4 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Bardet–Biedl syndrome (BBS) is an autosomal recessive disorder characterized by obesity, rod‐cone dystrophy, polydactyly, developmental delay, renal dysfunction, and genitourinary abnormalities. We report the case of a 27‐year‐old female with previously undiagnosed BBS who presented with acute kidney injury precipitated by acute ...
Aqeel Abbas +8 more
wiley +1 more source
Frontiers in Molecular Biosciences, 2017 Bardet-Biedl syndrome (BBS) is a rare genetic disorder that belongs to the group of ciliopathies, defined as diseases caused by defects in cilia structure and/or function. The six diagnostic features considered for this syndrome include retinal dystrophy,
María Álvarez-Satta +8 more
doaj +1 more source
Posttranslational Modifications of p62/SQSTM1 in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang +8 more
wiley +1 more source
Molecular Reproduction and Development, Volume 93, Issue 10, October 2026.ABSTRACT The aim of this study was to characterize the proteome of sperm and seminal plasma (SP) from rams with high semen freezability (HF) and low semen freezability (LF). Eleven ejaculates were collected from 12 rams, at 3‐day intervals, and cryopreserved (132 semen samples).
Wallisson Bruno de Morais Pacheco +14 more
wiley +1 more source
, 2011 Archaea are abundant in permanently cold environments. The Antarctic methanogen, Methanococcoides burtonii, has proven an excellent model for studying molecular mechanisms of cold adaptation.
Davide De Francisci +17 more
core +1 more source
CHIMIA, 2013 Proteins are macromolecules with a great diversity of functions. By combining these biomolecules with polymers, exciting opportunities for new concepts in polymer sciences arise.
Nico Bruns +5 more
doaj +1 more source
Controlling Geminiviruses before Transmission: Prospects
Plants, 2020 Whitefly (Bemisia tabaci)-transmitted Geminiviruses cause serious diseases of crop plants in tropical and sub-tropical regions. Plants, animals, and their microbial symbionts have evolved complex ways to interact with each other that impact their life ...
Muhammad Salman Mubarik +11 more
doaj +1 more source
Application of Omics Technologies for Cowpea Improvement
Plant-Environment Interactions, Volume 7, Issue 5, October 2026.ABSTRACT Cowpea (Vigna unguiculata) is a vital crop for food security, nutrition, and climate resilience in sub‐Saharan African and other semi‐arid regions. However, its improvement is constrained by the complexity of polygenic traits such as drought tolerance, pest resistance, and seed quality.
Junior S. Kamara +3 more
wiley +1 more source
Chaperonin of Group I: Oligomeric Spectrum and Biochemical and Biological Implications
Frontiers in Molecular Biosciences, 2018 Chaperonins play various physiological roles and can also be pathogenic. Elucidation of their structure, e.g., oligomeric status and post-translational modifications (PTM), is necessary to understand their functions and mechanisms of action in health and
Silvia Vilasi +13 more
doaj +1 more source