Results 81 to 90 of about 8,360 (214)
Controlling Geminiviruses before Transmission: Prospects
Whitefly (Bemisia tabaci)-transmitted Geminiviruses cause serious diseases of crop plants in tropical and sub-tropical regions. Plants, animals, and their microbial symbionts have evolved complex ways to interact with each other that impact their life ...
Muhammad Salman Mubarik +11 more
doaj +1 more source
How Salmonella Works Under Osmotic and Desiccation Stresses
ABSTRACT Salmonella remains one of the leading threats in foods with reduced water activity, where it can survive for long periods and cause outbreaks. Its persistence stems from a wide array of adaptive strategies shaped by the selective pressures imposed by low‐moisture foods.
Mayara Messias Oliveira +2 more
wiley +1 more source
Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication [PDF]
The major residual structure that remains associated with the nuclear envelope following extraction of isolated nuclei or oocyte germinal vesicles with non-ionic detergents, nucleases and high salt is the lamina (Fawcett, 1966; Aaronson and Blobel ...
Bridger, JM +3 more
core
Coherent Conformational Degrees of Freedom as a Structural Basis for Allosteric Communication [PDF]
Conformational changes in allosteric regulation can to a large extent be described as motion along one or a few coherent degrees of freedom. The states involved are inherent to the protein, in the sense that they are visited by the protein also in the ...
Mitternacht, Simon, Berezovsky, Igor N.
core +1 more source
Proteins are macromolecules with a great diversity of functions. By combining these biomolecules with polymers, exciting opportunities for new concepts in polymer sciences arise.
Nico Bruns +5 more
doaj +1 more source
ParPMC interactors were screened, highlighting eEF1A proteins; co‐localization and VIGS show their role in PPV infection and sharka susceptibility. ABSTRACT Sharka, caused by Potyvirus plumpoxi (plum pox virus, PPV), is the most destructive viral disease affecting Prunus species worldwide.
Ángela Polo‐Oltra +5 more
wiley +1 more source
Chaperonin of Group I: Oligomeric Spectrum and Biochemical and Biological Implications
Chaperonins play various physiological roles and can also be pathogenic. Elucidation of their structure, e.g., oligomeric status and post-translational modifications (PTM), is necessary to understand their functions and mechanisms of action in health and
Silvia Vilasi +13 more
doaj +1 more source
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin +12 more
wiley +1 more source
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria [PDF]
A nuclear encoded mitochondrial heat-shock protein hsp60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix.
Cheng, Ming Yuan +8 more
core +1 more source
ABSTRACT Clostridioides difficile (CD) is a leading cause of antibiotic‐associated diarrhoea in both hospitalized and non‐hospitalized patients. This study explores the role of extracellular vesicles (EVs) derived from Clostridioides difficile strain 630 (CD630‐EVs), which released spherical EVs during in vitro culture, in modulating pro‐inflammatory ...
Fangfang Fan +11 more
wiley +1 more source

