Results 121 to 130 of about 1,831,672 (338)
Applied SciencesParaxial beam modes, which propagate in space and focus without changing their transverse intensity pattern, are of great value for multiplexing transmitted data in optical communications, both in waveguides and in free space.
Eugeny G. Abramochkin +2 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
THE CHARACTERISTIC EQUATION FOR THE DETERMINATION OF THE VIBRATION INHERENT FREQUENCIES AT BENDING FROM TWO-SHAFTS TRANSMISSION [PDF]
Fiabilitate şi Durabilitate, 2018 To avoid system resonance operation is necessary to know the most accurate values its pulsations and taking appropriate constructive measures to avoid overlapping with disturbing frequency harmonics n,2n,3n (n the transmission speed).
Ion BULAC
doaj
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Critical Set of the Master Function and Characteristic Variety of the Associated Gauss–Manin Differential Equations [PDF]
, 2015 Alexander Varchenko
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
A NEW EQUATION FOR SIMULATING SOIL WATER CHARACTERISTIC CURVE [PDF]
, 2007 Basuony El-Garhy, Wail Omran
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Tamanoi Equation for Orbifold Euler Characteristics Revisited
Proceedings of the Steklov Institute of MathematicsTamanoi equation is a Macdonald type equation for the orbifold Euler characteristic and for its analogues of higher orders. It claims that the generating series of the orbifold Euler characteristics of a fixed order of analogues of the symmetric powers for a space with a finite group action can be represented as a certain unified (explicitly written ...
openaire +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
THE SOLUTION OF THE DARBOUX PROBLEM FOR THE TELEGRATH EQUATION WITH DEVIATION FROM THE CHARACTERISTIC [PDF]
, 2015 А. А. Akimov, G. Galiaskarova
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