Results 71 to 80 of about 8,865,093 (252)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Effect of polyethylene interface on space charge formation [PDF]
, 2004 This paper reports the results of an investigation into the space charge formation and decay at different material interfaces. In particular, the influence of the interface between electrode and polymer or polymer and polymer on the space charge dynamics
Tanaka, Y, Takada, T, Zhong, L, Chen, G
core +2 more sources
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Extremely Strong Halogen Bond. The Case of a Double-Charge-Assisted Halogen Bridge
, 2018 The stable model of a double (±)charge-assisted halogen bridge has been built on the basis of searches of the Crystal Structure Database. The model, investigated by DFT theory, consists of quinuclidine-like cation derivatives and a set of simple anions.
Marcin Palusiak (1472365) +2 more
core +1 more source
Interfacial Characteristics of Space Charge in Multi-layer LDPE [PDF]
, 2008 This paper reports on the investigation into space charge characteristics at interfaces of multi-layer polymeric materials. Planar low density polyethylene (LDPE) samples were used in this study. DC voltage up-to 10 kV was applied to the sample and space
Z. Xu +3 more
core +2 more sources
Multiple charge beam dynamics in alternate phase focusing structure
Physical Review Special Topics. Accelerators and Beams, 2014 Asymmetrical alternate phase (A-APF) focusing realized in a sequence of 36 superconducting quarter wave resonators (QWRs) has been shown to accelerate almost 81% of input uranium beam before foil stripper to an energy of 6.2 MeV/u from 1.3 MeV/u.
S. Dechoudhury +2 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Charge transfer-tuned magnetism in Nd-substituted Gd5Si4
AIP Advances, 2018 We report a charge-transfer mechanism in tuning of magnetism of Nd-substituted Gd5-xNdxSi4 (x=1 and 2.5) compounds. The X-ray absorption near edge structure measurements demonstrated that Nd substitutions for Gd induce charge transfer of 5d electrons ...
R. H. Kou +7 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source