Results 81 to 90 of about 3,110,538 (301)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Calculation of Blasting Damage Zone Radius of Different Charge Structures in Burnt Rock

Applied Sciences
The radius of the failure area after a blasting fracture process of burnt rock is affected by joint fissures, does not conform to the existing theoretical calculation formula and the distribution law of the failure area also changes. The fracture area is
Zhengzhao Jia, Hongjie Li, Wei Li, Jie Yan   +3 more
doaj   +1 more source

Charge order and phase segregation in overdoped bilayer manganites

, 2005
There have been recent reports of charge ordering around $x=0.5$ in the bilayer manganites. At $x=0.5$, there appears to be a coexistence region of layered A-type antiferromagnetc and charge order.
A Taraphder, Fujioka H, H Beck, Hirota K, Jackeli G, Kubota M, Maezono R, Qiu X, T Maitra, Wilkins S B   +9 more
core   +1 more source

Internal structure of charged AdS black holes [PDF]

Physical Review D, 2016
When an electrically charged black hole is perturbed its inner horizon becomes a singularity, often referred to as the Poisson-Israel mass inflation singularity. Ori constructed a model of this phenomenon for asymptotically flat black holes, in which the metric can be determined explicitly in the mass inflation region.
Bhattacharjee, Srijit, Sarkar, Sudipta, Virmani, Amitabh   +2 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Charge-density waves in one-dimensional Hubbard superlattices

, 2001
We study the formation of charge density waves (CDW's) in one-dimensional Hubbard superlattices, modeled by a repeated pattern of repulsive (U>0) and free (U=0) sites.
D. Jérome, E. Dagotto, E. Gagliano, E. Gagliano, G. Grüner, H. Frähm, H.H. Roomany, H.J. Schulz, H.L. Eßler, J. Silva-Valencia, J. Silva-Valencia, J. Solyom, J. Voit, J.E. Hirsch, J.E. Hirsch, J.E. Hirsch, M. Noh, P. Grünberg, Raimundo R. dos Santos, S. Brown, T. Paiva, T. Paiva, T. Paiva, T. Paiva, Thereza Paiva   +24 more
core   +1 more source

Molecular structure elucidation with charge-state control [PDF]

Science, 2019
Visualizing molecular charging High-resolution atomic force microscopy (AFM) has been used to control and image the charge state of organic molecules adsorbed on multilayer sodium chloride films. Fatayer et al. biased an AFM probe tip with a voltage to charge and discharge molecules such as azobenzene and ...
Fatayer, Shadi, Albrecht, Florian, Zhang, Yunlong, Urbonas, Darius, Peña, Diego, Moll, Nikolaj, Gross, Leo   +6 more
openaire   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Nuclear halo structure from quasielastic charge-exchange reactions

, 2005
Neutron and proton densities in the nuclear periphery are investigated within (p,n) charge-exchange isobar transitions. For this purpose we have developed parameter-free optical potentials with a detailed treatment of the in-medium $t_{\tau}$ part of the
Arellano, H. F., Love, W. G.
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source