Results 21 to 30 of about 70,844 (290)

A comparative evaluation of intraradicular smear removal efficacy of 2% chitosan (low molecular weight), 4% Chitosan Citrate, and 10% Citric Acid when Used as Final Rinse in Irrigation Protocols: A Field Emission Scanning Electron Microscopic Study

Journal of Pharmacy and Bioallied Sciences, 2017
Aim: This study aims to compare the smear layer removal efficacy of 2% chitosan (low molecular weight) (C-LMV), 4% chitosan citrate (CC), and 10% citric acid (CA) when used in specific irrigant protocols.
M Praveen, G Aarthi, P K Meenapriya, S Senthil Kumar, N S Mohan Kumar, J V Karunakaran   +5 more
doaj   +1 more source

Phosphorus Transformation in Soils Following Co-Application of Charcoal and Wood Ash

Agronomy, 2021
Phosphorus (P) is a vital soil macronutrient required by plants for optimum growth and development. However, its availability is limited because of fixation. The phosphorus fixation reaction is pH dependent.
Prisca Divra Johan, Osumanu Haruna Ahmed, Latifah Omar, Nur Aainaa Hasbullah   +3 more
doaj   +1 more source

Co-Application of Charcoal and Wood Ash to Improve Potassium Availability in Tropical Mineral Acid Soils

Agronomy, 2021
Potassium (K) is a macronutrient required by plants for energy production, enzyme activation, formation of cell wall, production of protein, and photosynthesis. However, K in the soil solution is leached from the rhizosphere before it interacts with soil
Puvan Paramisparam, Osumanu Haruna Ahmed, Latifah Omar, Huck Ywih Ch’ng, Prisca Divra Johan, Nur Hidayah Hamidi   +5 more
doaj   +1 more source

Sodium Thiosulfate: An Innovative Multi-Target Repurposed Treatment Strategy for Late-Onset Alzheimer’s Disease

Pharmaceuticals
Late-onset Alzheimer’s disease (LOAD) is a chronic, multifactorial, and progressive neurodegenerative disease that associates with aging and is highly prevalent in our older population (≥65 years of age).
Melvin R. Hayden, Neetu Tyagi
doaj   +1 more source

Cu²⁺-Chelating Mesoporous Silica Nanoparticles for Synergistic Chemotherapy/Chemodynamic Therapy

Pharmaceutics, 2022
In this study, a pH-responsive controlled-release mesoporous silica nanoparticle (MSN) formulation was developed. The MSNs were functionalized with a histidine (His)-tagged targeting peptide (B3int) through an amide bond, and loaded with an anticancer ...
Yanyan Zhang, Jiadong Lou, Gareth R. Williams, Yuhan Ye, Dandan Ren, Anhua Shi, Junzi Wu, Wenling Chen, Li-Min Zhu   +8 more
doaj   +1 more source

Interaction of 2,6,7-Trihydroxy-Xanthene-3-Ones with Iron and Copper, and Biological Effect of the Most Active Derivative on Breast Cancer Cells and Erythrocytes

Applied Sciences, 2020
Metal chelators can be potentially employed in the treatment of various diseases, ranging from metal overload to neoplastic conditions. Some xanthene derivatives were previously reported to complex metals.
Přemysl Mladěnka, Jana Karlíčková, Marcel Hrubša, Elma Veljović, Samija Muratović, Alejandro Carazo, Akash Shivling Mali, Selma Špirtović-Halilović, Luciano Saso, Milan Pour, Kemal Durić   +10 more
doaj   +1 more source

A Peptide-Based Trap for Metal Ions Studied by Electron Paramagnetic Resonance

Chemosensors, 2022
Peptide-based materials provide a versatile platform for sensing and ion sequestration since peptides are endowed with stimuli-responsive properties. The mechanism of molecular sensing is often based on peptide structural changes (or switching), caused ...
Victoria N. Syryamina, Alvaro S. Siano, Fernando Formaggio, Marta De Zotti   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Design, Synthesis, and Anti-Melanogenic Activity of 2-Mercaptomethylbenzo[d]imidazole Derivatives Serving as Tyrosinase Inhibitors: An In Silico, In Vitro, and In Vivo Exploration

Antioxidants
2-Mercaptomethylbenzo[d]imidazole (2-MMBI) derivatives were designed and synthesized as tyrosinase (TYR) chelators using 2-mercaptomethylimidazole scaffolds.
Hee Jin Jung, Hyeon Seo Park, Hye Jin Kim, Hye Soo Park, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon   +7 more
doaj   +1 more source

Research Advances in Cadmium Uptake, Transport and Resistance in Rice (Oryza sativa L.)

Cells, 2022
Rice (Oryza sativa L.) is one of the most important food crops, feeding half of the world’s population. However, rice production is affected by cadmium (Cd) toxicity.
Jialiang Zhang, Yanchun Zhu, Lijuan Yu, Meng Yang, Xiao Zou, Changxi Yin, Yongjun Lin   +6 more
doaj   +1 more source