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Advancement of scienceMyocardial infarction (MI), a consequence of coronary artery occlusion, triggers the degradation of ferritin, resulting in elevated levels of free iron in the heart and thereby inducing ferroptosis.
Q. Lv +9 more
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Pubertal Development in Girls with Beta Thalassaemia and Assessment of the Adequacy of Chelation Therapy: A Quasi-experimental Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Beta thalassaemia is the most prevalent hereditary autosomal disorder, significantly impacting endocrine function during pubertal development. The pathology is rooted in the excessive deposition of iron in vital organs.
Rupali Modak +3 more
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Surfactant function in neonates with respiratory distress syndrome [PDF]
, 1998 The function of pulmonary surfactant of a group of 14 preterm neonates (birth weight 907 +/- 60 g) who suffered from severe respiratory distress syndrome (RDS) and who had received exogenous bovine lipid extracted surfactant on the first day of life was ...
Griese, Matthias, Westerburg, Bettina
core +1 more source
Journal of HerbMed Pharmacology, 2019 Some heavy metals are nutritionally essential elements playing key roles in different physiological and biological processes, like: iron, cobalt, zinc, copper, chromium, molybdenum, selenium and manganese, while some others are considered as the ...
Reza Mehrandish +2 more
semanticscholar +1 more source
Thorium chelators for Targeted Alpha Therapy: Rapid chelation of thorium-226.
Journal of labelled compounds & radiopharmaceuticals, 2020 One of the main challenges in Targeted Alpha Therapy is assuring delivery of the α-particle dose to the targeted cells. Thus, it is critical to identify ligands for α-emitting radiometals that will form complexes which are very stable, both in vitro and ...
Maryline G. Ferrier +12 more
semanticscholar +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2020 Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni +8 more
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Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
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Scientific Reports, 2019 Medial arterial calcification (MAC) is a common outcome in diabetes and chronic kidney disease (CKD). It occurs as linear mineral deposits along the degraded elastin lamellae and is responsible for increased aortic stiffness and subsequent cardiovascular
Saketh R. Karamched +4 more
semanticscholar +1 more source
An update on iron chelation therapy. [PDF]
Blood transfusion = Trasfusione del sangue, 2012 Iron overload is a common clinical problem, arising from disorders of increased iron absorption such as hereditary haemochromatosis or thalassaemia intermedia syndromes or as a consequence of chronic blood transfusions for various blood disorders. Regular red blood cell (RBC) transfusions are the principal supportive therapy for many rare anaemias ...
E. Poggiali +3 more
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Hematology, Transfusion and Cell Therapy, 2023 Introduction: Magnetic resonance imaging (MRI) T2* technique is used to assess iron overload in the heart, liver and pancreas of thalassaemic patients. Optimal iron chelation and expected tissue iron response rates remain under investigation.
Eduardo Cerello Chapchap +17 more
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