Results 121 to 130 of about 4,406,721 (399)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Abundance Ratios of OH/CO and HCO+/CO as Probes of the Cosmic-Ray Ionization Rate in Diffuse Clouds

open access: yesThe Astrophysical Journal, 2023
The cosmic-ray ionization rate (CRIR, ζ _2 ) is one of the key parameters controlling the formation and destruction of various molecules in molecular clouds. However, the current most commonly used CRIR tracers, such as ${{\rm{H}}}_{3}^{+}$ , OH ^+ , and
Gan Luo   +8 more
doaj   +1 more source

CHEMICAL ABUNDANCES IN A SAMPLE OF RED GIANTS IN THE OPEN CLUSTER NGC 2420 FROM APOGEE [PDF]

open access: yes, 2016
NGC 2420 is a ∼2 Gyr old well-populated open cluster that lies about 2 kpc beyond the solar circle, in the general direction of the Galactic anti-center.
D. Souto   +22 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Model reduction for stochastic chemical systems with abundant species [PDF]

open access: yes, 2015
Biochemical processes typically involve many chemical species, some in abundance and some in low molecule numbers. Here we first identify the rate constant limits under which the concentrations of a given set of species will tend to infinity (the abundant species) while the concentrations of all other species remains constant (the non-abundant species).
arxiv   +1 more source

CHAOS I. DIRECT CHEMICAL ABUNDANCES FOR H II ?> REGIONS IN NGC 628 [PDF]

open access: yes, 2015
The CHemical Abundances of Spirals (CHAOS) project leverages the combined power of the Large Binocular Telescope (LBT) with the broad spectral range and sensitivity of the Multi Object Double Spectrograph (MODS) to measure “direct” abundances (based on ...
D. Berg   +5 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

The abundance discrepancy in ionized nebulae: which are the correct abundances? [PDF]

open access: yesarXiv, 2023
Ionized nebulae are key to understanding the chemical composition and evolution of the Universe. Among these nebulae, H~{\sc ii} regions and planetary nebulae are particularly important as they provide insights into the present and past chemical composition of the interstellar medium, along with the nucleosynthetic processes involved in the chemical ...
arxiv  

Chemical abundances in a UV-selected sample of galaxies [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2002
17 pages, 10 figures, and 2 tables.
Contini, Thierry   +3 more
openaire   +6 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

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