Results 121 to 130 of about 4,382,200 (272)

BBN and the Primordial Abundances

, 2005
The relic abundances of the light elements synthesized during the first few minutes of the evolution of the Universe provide unique probes of cosmology and the building blocks for stellar and galactic chemical evolution, while also enabling constraints ...
C. Chiappini, D. Kirkman, D.N. Spergel, G. Steigman, G. Steigman, I. Iben, J. Lequeux, J. Melendez, J.A. Thorburn, J.N. Bahcall, J.P. Kneller, K.A. Olive, L. Randall, M. Kawasaki, M.H. Pinsonneault, P. Bonifacio, R.T. Rood, S. Cassisi, S.G. Ryan, S.M. Viegas, T.M. Bania, V. Barger   +21 more
core   +2 more sources

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Volatiles and refratories in solar analogs: no terrestial planet connection

, 2010
We have analysed very high-quality HARPS and UVES spectra of 95 solar analogs, 24 hosting planets and 71 without detected planets, to search for any possible signature of terrestial planets in the chemical abundances of volatile and refractory elements ...
Elisa Delgado-Mena, Garik Israelian, Jonay I. González Hernández, Neves, Nuno C. Santos, Ramírez, Ramírez, Sergio Sousa, Sousa, Stéphane Udry, Vasco Neves   +10 more
core   +1 more source

Chemical abundances of Seyfert 2 AGNs – III. Reducing the oxygen abundance discrepancy [PDF]

, 2020
O. L. Dors, R. Maiolino, M. V. Cardaci, G. F. Hägele, A. C. Krabbe, E. Pérez‐Montero, Mark Armah   +6 more
openalex   +1 more source

Atomic Diffusion and Mixing in Old Stars VIII: Chemical abundance variations in the globular cluster M4 (NGC 6121) [PDF]

, 2023
Thomas Nordlander, Pieter Gruyters, O. Richard, A. J. Korn   +3 more
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Rapid Chemical Enrichment by Intermittent Star Formation in GN-z11

The Astrophysical Journal Letters
We interpret the peculiar supersolar nitrogen abundance recently reported by the James Webb Space Telescope observations for GN-z11 ( z = 10.6) using our state-of-the-art chemical evolution models.
Chiaki Kobayashi, Andrea Ferrara
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The High-Redshift Gas-Phase Mass–Metallicity Relation in FIRE-2

The Astrophysical Journal Letters
The unprecedented infrared spectroscopic capabilities of JWST have provided high-quality interstellar medium metallicity measurements and enabled characterization of the gas-phase mass–metallicity relation (MZR) for galaxies at z ≳ 5 for the first time ...
Andrew Marszewski, Guochao Sun, Claude-André Faucher-Giguère, Christopher C. Hayward, Robert Feldmann   +4 more
doaj   +1 more source