Results 61 to 70 of about 92,867 (160)

Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue

The Korean Journal of Gastroenterology, 2020
Hepatic disorders with prominent cholestasis can be caused by a range of conditions, and anabolic androgenic steroids have been considered a cause of protracted cholestasis.
Hyun Gil Goh, Yoo Jin Lee, Tae Hyung Kim
doaj   +1 more source

Serum markers for detecting histological features of autoimmune hepatitis and predicting prognosis in patients with antinuclear antibody‐positive drug‐induced liver injury

Portal Hypertension & Cirrhosis
Aims Although useful for distinguishing drug‐induced liver injury (DILI) from autoimmune hepatitis (AIH), liver biopsy is an invasive examination, and the presence of antinuclear antibody (ANA) positivity in patients with DILI could lead to excessive use
Feiyu Zhang, Meishan Jin, Hongqin Xu, Peng Xiao, Yanhang Gao   +4 more
doaj   +1 more source

The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States Are Frequently Mislabeled

Hepatology Communications, 2019
The U.S. Drug Induced Liver Injury Network assayed the contents of herbal and dietary supplements collected from patients enrolled into its prospective study.
Victor Navarro, Bharathi Avula, Ikhlas Khan, Manisha Verma, Leonard Seeff, Jose Serrano, Andrew Stolz, Robert Fontana, Jawad Ahmad   +8 more
doaj   +1 more source

Hepatoprotective Effects of Curcumin and Thymoquinone Against Chemically Induced Liver Injury: A Schematic Study with Meta-Analysis of Antioxidant and Anti-inflammatory Outcomes

Pakistan Journal of Medicine and Dentistry
Background: Curcumin and thymoquinone are phytochemicals that have shown the ability to protect the liver in previous studies, with involvement of their antioxidant and anti-inflammatory activity. This study aimed to examine the effective concentrations
Madiha Niamat, Mohammad Abid, Abdul Rehman Khalil Shaikh, Sana Masood, Fiza   +4 more
doaj   +1 more source

Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state

Scientific Reports
Chronic liver injury induces fibrosis that often proceeds to cirrhosis and hepatocellular carcinoma, indicating that prevention and/or resolution of fibrosis is a promising therapeutic target.
Yasuhiro Nakano, Eiko Saijou, Tohru Itoh, Minoru Tanaka, Atsushi Miyajima, Taketomo Kido   +5 more
doaj   +1 more source

Drug-induced liver injury in children: A nationwide cohort study from China

JHEP Reports
Background & Aims: Currently, there is limited knowledge on the clinical profile of drug-induced liver injury (DILI) in Chinese children. We aimed to assess the clinical characteristics, suspected drugs, and outcomes associated with pediatric DILI in
Rongtao Lai, Xinjie Li, Jie Zhang, Jun Chen, Changqing Yang, Wen Xie, Yuecheng Yu, Xiaoyan Guo, Xinrong Zhang, Guoliang Lu, Xi’an Han, Qing Xie, Chengwei Chen, Tao Shen, Yimin Mao   +14 more
doaj   +1 more source

Molecular network-based analysis of the mechanism of liver injury induced by volatile oils from Artemisiae argyi folium

BMC Complementary and Alternative Medicine, 2017
Background Volatile oils from Artemisiae argyi folium (VOAAF) is reported with hepatotoxicity, but the underlying mechanism is still unclear. Methods In the present study this molecular mechanism was explored with the Ingenuity Pathway Analysis (IPA ...
Hongjie Liu, Sha Zhan, Yan Zhang, Yan Ma, Liang Chen, Lingxiu Chen, Hanqiu Dong, Min Ma, Zhe Zhang   +8 more
doaj   +1 more source

Liver Multiacinar Regenerative Nodules: Imaging Findings and Clinical Implications

Acta Médica Portuguesa, 2018
Introduction: Multiacinar regenerative nodules are benign hepatocellular nodules related to vascular disturbances of the liver. They strongly resemble conventional focal nodular hyperplasia but are connected to different clinical settings, typically ...
Henrique Donato, Luísa Andrade, Nina Bastati, Augusta Cipriano, Ahmed Ba-Ssalamah, Filipe Caseiro-Alves   +5 more
doaj   +1 more source

Development on Animal Models for Drug/Chemical Induced Liver Injury

, 2023
D. S. Bhatia, Yogeeta Yogeeta, Pradeep Goyal, Atul Kabra   +3 more
openalex   +1 more source

Antioxidant and hepatoprotective effect of Jatropha dioica against the valproic acid-induced damage in an in vivo model

BMC Complementary Medicine and Therapies
Background Understanding liver diseases is important worldwide due to their prevalence. Apart from liver disease arising from hepatitis C viral infection, most chronic liver diseases currently have no cure.
Paula Cordero-Pérez, Ramiro Tijerina-Márquez, Veronica Mayela Rivas-Galindo, Liliana Torres-González, Diana Raquel Rodríguez-Rodríguez, Oscar Humberto Mendoza-Hernández, César Bigran Espinosa-Cantú, Guadalupe Yazmín Solís-Cruz, Linda E. Muñoz-Espinosa, Edelmiro Pérez-Rodríguez, Idalia Cura-Esquivel, Gabriela Alarcón-Galván, Diana Patricia Moreno-Pena   +12 more
doaj   +1 more source