Results 61 to 70 of about 74,439 (262)

Analysis of risk factors of liver injury after intravenous methylprednisolone in neuromyelitis optica spectrum disorders

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Objective To investigate the risk factors of liver injury in patients with neuromyelitis optica spectrum disorders (NMOSDs) after intravenous methylprednisolone (IVMP).
YANG Qing⁃lin , LIU Peng⁃peng, WANG Jia⁃wei   +2 more
doaj   +1 more source

Additional file 3 of Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure

, 2021
Additional file 3: Figure S2. DILI label prediction performance (balanced accuracy) of RF and SVM models trained using the DILIrank (−vLessConcern) dataset and protein target descriptors for 5-fold LOCO-CV, external test set, and FDA validation set (Methods).
Liu, Anika, Walter, Moritz, Wright, Peter, Bartosik, Aleksandra, Dolciami, Daniela, Elbasir, Abdurrahman, Hongbin Yang, Bender, Andreas   +7 more
openaire   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Pantoprazole-Induced Liver Injury in the Setting of Diabetic Ketoacidosis

Acta Médica Portuguesa
N/a.
Raquel Oliveira, Manuel Almeida, Pedro Lavado, Alexandre Baptista   +3 more
doaj   +1 more source

Additional file 1 of Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure

, 2021
Additional file 1: SI. Overview of gene expression data preparation, DILI model generation, and DILI label prediction performance for models derived using L1000 gene expression data. Gene expression data for 14 distinct cell line-time-dose combinations was extracted for all compounds with DILI labels.
Liu, Anika, Walter, Moritz, Wright, Peter, Bartosik, Aleksandra, Dolciami, Daniela, Elbasir, Abdurrahman, Hongbin Yang, Bender, Andreas   +7 more
openaire   +2 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Circulating liver-specific miR-122 as a novel potential biomarker for diagnosis of cholestatic liver injury. [PDF]

PLoS ONE, 2013
BACKGROUND: Circulating microRNA-122 (miR-122) has been increasingly reported to be a potential biomarker for drug-, viral-, alcohol- and chemical-induced liver injury.
Huang Shifeng, Wang Danni, Chen Pu, Yang Ping, Cao Ju, Zhang Liping   +5 more
doaj   +1 more source

[Drug induced liver injury. Chemical liver necrosis caused by formation of reactive metabolites].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976
Erik Dybing
openalex   +2 more sources

Additional file 7 of Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure

, 2021
Additional file 7: TableS2. Proteins with high feature importance in RF and SVM, and links to DILI. The 19 proteins with the highest feature importance in RF or SVM models are shown. The feature importance is shown in bold if the protein ranked among the top 19 in the respective model.
Liu, Anika, Walter, Moritz, Wright, Peter, Bartosik, Aleksandra, Dolciami, Daniela, Elbasir, Abdurrahman, Hongbin Yang, Bender, Andreas   +7 more
openaire   +2 more sources

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source