Results 121 to 130 of about 596,259 (322)

Characterization of Physical and Chemical Properties of Functional Beverages of Robusta Coffee Leaf Herbal Tea With Red Ginger-Enriched Green Tea Technique

, 2023
Fahmi Arifan, Wisnu Broto, Edy Supriyo, Mirza Muhammad Faisal, Oktaviani Kusuma Wardani, Enrico Fendy Sapatra   +5 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Unveiling Galaxy Chemical Enrichment Mechanisms Out to z ∼ 8 from Direct Determination of O and Ar Abundances from JWST/NIRSPEC Spectroscopy

The Astrophysical Journal Letters
Galaxy chemical enrichment mechanisms have primarily been constrained by [ α /Fe] and [Fe/H] measurements of individual stars and integrated light from stellar populations. However, such measurements are limited at higher redshifts ( z  > 1).
Souradeep Bhattacharya, Magda Arnaboldi, Ortwin Gerhard, Chiaki Kobayashi, Kanak Saha   +4 more
doaj   +1 more source

Evaluating the wettability of coal and non-coal mineral particles by microcalorimetry

Fuel Processing Technology
The surface wettability of coal and non-coal minerals is one of the critical factors influencing their separation and processing. In this study, ten common coal and non-coal minerals were selected to analyze the quantitative relationship between their ...
Chengping Deng, Zhongzheng Wu, Teng He, Yuqiang Mao, Liuyang Dong, Dianwen Liu   +5 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Metallicities from High-resolution TRES Spectra with uberMS: Performance Benchmarks and Literature Comparison

The Astrophysical Journal Supplement Series
As the field of exoplanetary astronomy has matured, demand has grown for precise stellar abundances to probe subtle correlations between stellar compositions and planetary demographics.
Emily K. Pass, Phillip A. Cargile, Victoria DiTomasso, Romy Rodríguez Martínez, David Charbonneau, David W. Latham, Andrew Vanderburg, Allyson Bieryla, Samuel N. Quinn, Lars A. Buchhave   +9 more
doaj   +1 more source

Ethno-STEM-Integrated Enriched Chemistry Book to Equip Chemical and Numeracy Literacy

Journal of Innovation in Educational and Cultural Research
Students in Indonesia face chemical literacy and numeracy challenges, which are essential for understanding scientific concepts and solving real-world problems.
Amroeni Rosyada, Woro Sumarni, Murbangun Nuswowati, Ade Noorliza Niyamae   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

PROCESSING AND ENRICHMENT OF YELLOW MAIZE GRITS WITH LEGUMES ON THE PRODUCED EXTRUDATES: I. CHEMICAL EVALUATION. [PDF]

, 1995
Ahmed M. Kassem, SAEED M. MANSOUR, Nesma Ali Ibrahim   +2 more
openalex   +1 more source