Results 111 to 120 of about 1,651,742 (317)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Concrete Chemical Evolution [PDF]

, 1998
The objectives of this analysis are to discuss and evaluate testing results that were performed for the M&O by the Pennsylvania State University (PSU) to evaluate the potential long-term evolution of organic admixtures in cementitious materials at elevated temperatures.
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Chemical evolution of primordial salts and organic sulfur molecules in the asteroid 162173 Ryugu. [PDF]

Nat Commun, 2023
Yoshimura T, Takano Y, Naraoka H, Koga T, Araoka D, Ogawa NO, Schmitt-Kopplin P, Hertkorn N, Oba Y, Dworkin JP, Aponte JC, Yoshikawa T, Tanaka S, Ohkouchi N, Hashiguchi M, McLain H, Parker ET, Sakai S, Yamaguchi M, Suzuki T, Yokoyama T, Yurimoto H, Nakamura T, Noguchi T, Okazaki R, Yabuta H, Sakamoto K, Yada T, Nishimura M, Nakato A, Miyazaki A, Yogata K, Abe M, Okada T, Usui T, Yoshikawa M, Saiki T, Tanaka S, Terui F, Nakazawa S, Watanabe SI, Tsuda Y, Tachibana S, Hayabusa2-initial-analysis SOM team.   +43 more
europepmc   +1 more source

Chemical Evolution of the Carina Dwarf Spheroidal

, 2012
We explore a range of chemical evolution models for the Local Group dwarf spheroidal (dSph) galaxy, Carina. A novel aspect of our work is the removal of the star formation history (SFH) as a `free parameter' in the modeling, making use, instead, of its ...
Gibson, B. K., Pilkington, K.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Chemical evolution of an autonomous DNAzyme with allele-specific gene silencing activity. [PDF]

Nat Commun, 2023
Nguyen K, Malik TN, Chaput JC.
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Ryugu asteroid sample return provides a natural laboratory for primordial chemical evolution. [PDF]

Nat Commun, 2023
Oba Y, Takano Y, Dworkin JP, Naraoka H.
europepmc   +1 more source