Results 221 to 230 of about 652,135 (265)

Chemical methods for modification of proteins

Organic & Biomolecular Chemistry, 2020
The field of protein bioconjugation draws attention from stakeholders in chemistry, biology, and medicine. This review provides an overview of the present status, challenges, and opportunities for organic chemists.
Neelesh C. Reddy, Mohan Kumar, Rajib Molla, Vishal Rai   +3 more
openaire   +2 more sources

THE CHEMICAL MODIFICATION OF ENZYMATIC SPECIFICITY

Annual Review of Biochemistry, 1985
The chemical modification of enzymes has played and will continue to play an important role in probing the mechanism of enzyme activity. This technique can be utilized for identification of those individual amino acid residues responsible for the catalytic properties of the entire protein.
E T, Kaiser, D S, Lawrence, S E, Rokita
openaire   +2 more sources

Acid glycosaminoglycans and their chemical modification

Russian Journal of Bioorganic Chemistry, 2008
The modem state of chemical modification of hyaluronic acid, chondroitin sulfates, and heparin is considered, and the possible application of modified glycosaminoglycans as potential drugs is discussed.
I Iu, Ponedel'kina, E S, Lukina, V N, Odinokov   +2 more
openaire   +2 more sources

Chemical Modification of Proteins

2003
The two most widely used applications for chemical modification are in primary structure analysis and in the identification of essential groups involved in the binding and catalytic sites of proteins. The methods discussed here are those used frequently in primary structure analysis.
openaire   +3 more sources

Implications of the chemical modification of chymotrypsin

Biochemical and Biophysical Research Communications, 1973
Abstract The short N-terminal chain of δ-chymotrypsin, a two-chain member of the chymotrypsin family, was removed by reduction. The residual reduced major chain exhibited significant enzymic activity after refolding at low pH had occurred, and most of the native activity was regained upon subsequent oxidation.
S M, Grey, G R, Nurse, L, Visser
openaire   +2 more sources

The Chemical Modification of Nucleic Acids

1969
Publisher Summary This chapter describes chemical modification of nucleic acids. Modification of the units of polymer chains by reaction with chemical agents is one of the promising methods for studying the structure and function of biopolymers, particularly polynucleotides.
N K, Kochetkov, E I, Budowsky
openaire   +2 more sources

chemical modification

2021
Seyedeh Maryam Mortazavi, Hamid R. Moghimi, Howard I. Maibach   +2 more
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Recent Advances in Biocatalysis with Chemical Modification and Expanded Amino Acid Alphabet

Chemical Reviews, 2021
Philip Dawson, Mahesh D Patil, Dillon Flood   +2 more
exaly  

Chemical Modification of Proteoglycanases with Biotin

2019
Biotinylation is a versatile technique that has been used to label proteins for a variety of applications. Under alkaline conditions, the N-hydroxylsuccinimide (NHS) ester present on the biotinylation reagent reacts with primary amines such as the side chain of lysine residues or the N-termini of proteins to yield stable amide bonds.
openaire   +3 more sources

Hemicellulose: Structure, chemical modification, and application

Progress in Polymer Science, 2023
Feng Peng, Ziwen Lv, Gegu Chen
exaly