Results 31 to 40 of about 650,908 (266)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Biomimetic Bouligand chiral fibers array enables strong and superelastic ceramic aerogels

open access: yesNature Communications
Ceramic aerogels are often used when thermal insulation materials are desired; however, they are still plagued by poor mechanical stability under thermal shock.
Hongxing Wang   +4 more
doaj   +1 more source

Silkworm Self-spun Fluorescent Silk Fiber with Enhanced Mechanical Properties

open access: yesJournal of Natural Fibers, 2022
Silk fiber (SF) is a well-known natural material broadly applied for the common textile industry and modern medical field cases. This work introduces a simple process for silkworm self-spun producing fluorescent silk fiber (FSF) with enhanced strength ...
Lin-Hai Jiang, Qing Shen
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Skin-Inspired Self-Adaptive System for Temperature Control During Dynamic Wound Healing

open access: yesNano-Micro Letters
Highlights An interactive electronic system inspired by the temperature self-regulation of human skin. Heat stimulation therapy and temperature monitoring during dynamic wound healing. Mechanism of temperature self-regulation during dynamic wound healing.
Yaqi Geng   +9 more
doaj   +1 more source

Self-organization of unimolecular micelles in beam stream for functional mesoporous metal oxide nanofibers

open access: yesFundamental Research, 2022
The use of linear amphiphilic block copolymers as templates is an important method for the preparation of mesoporous materials. However, the obtained assemblies are usually sensitive to synthetic conditions, which impedes the preparation of such ...
Chongfei Gu   +12 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An elastic piezoelectric nanomembrane with double noise reduction for high-quality bandpass acoustics

open access: yesNature Communications
Polymer piezoelectrics with high electromechanical energy conversion (HEEC) are very promising for flexible acoustoelectric devices. However, reducing thickness and improving ordered polarization and ferroelectricity while maintaining high mechanical ...
Jialin Zhang, Yanjun Liu, Peiyi Wu
doaj   +1 more source

A Robust Hierarchical MXene/Ni/Aluminosilicate Glass Composite for High‐Performance Microwave Absorption

open access: yesAdvanced Science, 2022
The 2D titanium carbide MXene with both extraordinary electromagnetic attenuation and elastic properties has shown great potential as the building block for constructing mechanically robust microwave absorbing composites (MACs). However, the weak thermal
Wei Luo   +12 more
doaj   +1 more source

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