Results 51 to 60 of about 1,570,001 (303)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Skin-Inspired Self-Adaptive System for Temperature Control During Dynamic Wound Healing
Nano-Micro LettersHighlights An interactive electronic system inspired by the temperature self-regulation of human skin. Heat stimulation therapy and temperature monitoring during dynamic wound healing. Mechanism of temperature self-regulation during dynamic wound healing.
Yaqi Geng +9 more
doaj +1 more source
Advanced Science, 2022 The 2D titanium carbide MXene with both extraordinary electromagnetic attenuation and elastic properties has shown great potential as the building block for constructing mechanically robust microwave absorbing composites (MACs). However, the weak thermal
Wei Luo +12 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Aerogel-based Leidenfrost vapor percolator for ultra-fast thermal cooling
Nature CommunicationsThe Leidenfrost effect—where liquid droplets levitate on superheated surfaces—hinders efficient heat transfer. Conventional mitigation strategies typically rely on rigid materials with complex surface engineering, but their applicability is limited by ...
Hongxing Wang +6 more
doaj +1 more source
Chemical modification of poly(p-phenylene) for use in ablative compositions [PDF]
, 1972 Development of ablative materials based on modification of polyphenylene compounds is discussed. Chemical and physical properties are analyzed for application as heat resistant materials. Synthesis of linear polyphenylenes is described.
Hammermesh, C. L. +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Efficiency at maximum power of a chemical engine
, 2013 A cyclically operating chemical engine is considered that converts chemical energy into mechanical work. The working fluid is a gas of finite-sized spherical particles interacting through elastic hard collisions.
Broeck, Christian Van den +4 more
core +1 more source
5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6- (3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one [PDF]
, 2018 Natural and semi-synthetic compounds are being studied as novel phosphodiesterase 5 (PDE5) inhibitors for the treatment of erectile dysfunction, pulmonary hypertension, and lower urinary symptoms.
Ongaro, Alberto +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source