Results 91 to 100 of about 3,962,606 (332)
A manteiga de garrafa é um produto largamente utilizado no Nordeste do Brasil em geral, e no norte/nordeste do Estado de Minas Gerais em particular, sendo a região de Salinas importante produtora desse tipo de manteiga.
Maria das Graças Clemente +1 more
doaj +1 more source
The quality of honey without stings can be seen from its physical, chemical properties and the absence of heavy metals. The purpose of this study was to evaluate the physicochemical and heavy metals content of Heterotrigona itama stingless honey at a ...
Saputra S.H., Nurlina S.
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
This study successfully analyzed the reverse osmosis (RO) separation performances of ethanol/water mixture (1–37 wt% of ethanol) with polymeric RO membranes using transport equations derived on the basis of the solution-diffusion mechanism in which the ...
Kazuki Akamatsu +3 more
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
The present study evaluates the physicochemical attributes, antibacterial efficacy, and antioxidant capacities of four distinct varieties of honey from the West Bank region of Palestine: Assal Barsem (Medicago sativa) AB, Assal Morar (Centaurea dumulosa ...
Basheer Abu-Farich +7 more
doaj +1 more source
Properties of Yak Wool in Comparison to Cashmere and Camel Hairs
Recently, yak wool has got more and more attentions for its good quality and competitive price in textile industry. However, for its large dispersion and stiffness, there are still some difficulties in utilizing yak fibers, which also further limit the ...
Chan Liu, Chunping Xie, Xinjin Liu
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source

