Results 61 to 70 of about 531 (218)

Stellar nucleosynthesis in the era of large surveys: S-process-polluted binaries in GALAH DR4

open access: yesAstronomy & Astrophysics
Context. Binary interactions during the asymptotic giant branch phase can lead to the formation of chemically peculiar stars such as Ba-, CH-, and CEMP-s stars with overabundances of s-process elements as well as carbon. Only a few hundred of these stars
Escorza A.   +13 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

On the 3He anomaly in hot subdwarf B stars

open access: yesOpen Astronomy, 2017
Decades ago, 3He isotope enrichment in helium-weak B-type main-sequence, in blue horizontal branch and in hot subdwarf B (sdB) stars, i.e., helium-core burning stars of the extreme horizontal branch, were discovered. Diffusion processes in the atmosphere
Schneider David   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

An Unsupervised Machine Learning Approach to Identify Spectral Energy Distribution Outliers: Application to the S-PLUS DR4 Data

open access: yesThe Astronomical Journal
Identification of specific stellar populations using photometry for spectroscopic follow-up is a first step to confirm and better understand their nature.
F. Quispe-Huaynasi   +15 more
doaj   +1 more source

HST spectroscopy of chemically peculiar hot subdwarfs: PG 0909+276 and UVO0512–08

open access: yesOpen Astronomy, 2017
High-resolution ultraviolet spectroscopy of two chemically peculiar hot subdwarfs, PG 0909+276 and UVO0512-08, has been obtained using the Hubble Space Telescope.
Wild James, Jeffery Christopher Simon
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Carbon Stars from Gaia Data Release 3 and the Space Density of Dwarf Carbon Stars

open access: yesThe Astrophysical Journal
Carbon stars (with atmospheric C/O > 1) range widely in temperature and luminosity, from low-mass dwarfs to asymptotic giant branch (AGB) stars. The main-sequence dwarf carbon (dC) stars have inherited carbon-rich material from an AGB companion, which ...
Benjamin R. Roulston   +3 more
doaj   +1 more source

Unveiling the nature of barium stars

open access: yesAstronomy & Astrophysics
Context. Barium star systems are excellent sites for studying asymptotic giant branch (AGB) nucleosynthesis, binary evolution, and mass transfer processes. However, an accurate estimation of their fundamental stellar parameters is still lacking. Aims. We
Sarmah Lupamudra   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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