Results 91 to 100 of about 8,108,131 (288)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Synthesis, structure and pyrolysis of stabilised phosphonium ylides containing saturated oxygen heterocycles [PDF]

, 2016
A range of twelve stabilised phosphonium ylides containing tetrahydrofuran, tetrahydropyran or 2,2-dimethyl-1,3-dioxolane rings have been prepared and fully characterised, including one X-ray structure determination of each type.
Sahabo, Nina Carole, Rouxel, C., McCarron, Hollie B, Slawin, Alexandra Martha Zoya, Aitken, Robert Alan, Karodia, Nazira, McCarron, H.B., Rouxel, Cécile, Aitken, R.A., Slawin, A.M.Z., Sahabo, Nina   +10 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Chemistry, Metabolism, and Toxicology of Cannabis: Clinical Implications

Iranian Journal of Psychiatry, 2012
Cannabis is one of the most widely abused substances throughout the world. The primary psychoactive constituent of cannabis, delta 9-tetrahydrocannabinol (Δ9_THC), produces a myriad of pharmacological effects in animals and humans. Although it is used as
M.M. Srinivas Bharath, Pratima Murthy, Priyamvada Sharma   +2 more
doaj   +2 more sources

Instrumental Analysis, Automation and Robotics in Clinical Chemistry Instrumentalanalyse, Automation und Robotics in der Klinischen Chemie

CHIMIA, 2001
Clinical chemistry is probably the part of analytical chemistry which is under the greatest pressure with respect to productivity. This results in methods completely different from those used in classical analytical chemistry. Separation methods
Dieter J. Vonderschmitt
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Impact of Microcystin-LR on Liver Function Varies by Dose and Sex in Mice

Toxins, 2018
Microcystin (MC) exposure is an increasing concern because more geographical locations are covered with cyanobacterial blooms as eutrophication and bloom-favoring environmental factors become more prevalent worldwide. Acute MC exposure has been linked to
Igor Mrdjen, Mark A. Morse, Randall J. Ruch, Thomas J. Knobloch, Shambhunath Choudhary, Christopher M. Weghorst, Jiyoung Lee   +6 more
doaj   +1 more source

Quantities and Units in Clinical Chemistry [PDF]

Methods of Information in Medicine, 1968
The author describes the efforts of the »Commission on Clinical Chemistry« of IUPAC and IFCC to standardize the concepts, symbols and units used in the clinical laboratory which is a presupposition for an international comparability of laboratory data. The proposals of the commission have been published in a Recommendation 1966.
openaire   +9 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Graduate Study in Chemistry, The University of Texas at Austin, circa 1977

, 1977
Table of Contents: Foreword (p. 3) -- The University (p. 4) -- The Austin Community (p. 6) -- Texas and Central Texas (p. 10) -- The Chemistry Department (p. 14) -- Research Specializations (p. 20-81) -- Analytical Chemistry (p.
Chemistry Department
core   +1 more source