Results 111 to 120 of about 556,392 (291)

IFCC educational materials on selected analytical and clinical applications of high sensitivity cardiac troponin assays.

, 2015
In 2011, the IFCC Task Force on Clinical Applications of Cardiac Bio-Markers (TF-CB) was formed, with the purpose of providing evidence based educational materials to assist all biomarker users, i.e.
Than M, Lindahl B, Apple FS, PLEBANI, MARIO, Jaffe AS, Chan MH, Collinson P, Ordonez Llanos J, Hollander J, International Federation of Clinical Chemistry Task Force on Clinical Applications of Cardiac Bio Markers, Mockel M   +10 more
core   +1 more source

Comparison of two different technologies measuring the same analytes in view of the In Vitro Diagnostic Regulation (IVDR)

Journal of Laboratory Medicine
This study systematically compared the performance and comparability of two medical laboratory analytical instruments, the conventional wet chemistry analyzer (cobas) and the dry slide technology (Vitros), across various clinical chemistry assays.
Stierlin Noel, Hemmerle Andreas, Jung Karin, Thumfart Jörg, Risch Martin, Risch Lorenz   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Clinical chemistry lookout.

Swedish society of clinical ...
Swedish society for clinical chemistry
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Review of Four centuries of clinical chemistry, Louis Rosenfeld

, 2001
Review of Four Centuries of Clinical Chemistry, Louis ...
Meites, Samuel
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Insights from semi-structured interviews on integrating artificial intelligence in clinical chemistry laboratory practices

BMC Medical Education
Background Artificial intelligence (AI) is gradually transforming the practises of healthcare providers. Over the last two decades, the advent of AI into numerous aspects of pathology has opened transformative possibilities in how we practise laboratory ...
Lena Jafri, Arsala Jameel Farooqui, Janet Grant, Usmaan Omer, Rodney Gale, Sibtain Ahmed, Aysha Habib Khan, Imran Siddiqui, Farooq Ghani, Hafsa Majid   +9 more
doaj   +1 more source

Protocol for assessing total antioxidant capacity in minimal volumes of varying clinical human samples

STAR Protocols
Summary: Total antioxidant capacity (TAC), representative of the capacity to combat oxidative stress, is closely linked to numerous diseases. Here, we present a protocol for measuring TAC using minimal samples that are stable across varying pH levels and
Yu-Ting Tsao, Yi-Jen Hsueh, Hung-Chi Chen, Chao-Min Cheng   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Clinical microscopy and chemistry,

, 1919
Mode of access ...
McJunkin, Frank Adam, 1882-
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