Results 11 to 20 of about 10,692 (235)

Citrus hystrix Extracts Protect Human Neuronal Cells against High Glucose-Induced Senescence

Pharmaceuticals, 2020
Citrus hystrix (CH) is a beneficial plant utilized in traditional folk medicine to relieve various health ailments. The antisenescent mechanisms of CH extracts were investigated using human neuroblastoma cells (SH-SY5Y).
Nattaporn Pattarachotanant, Tewin Tencomnao   +1 more
doaj   +1 more source

Anacardium Occidentale L. Leaf Extracts Protect Against Glutamate/H2O2-Induced Oxidative Toxicity and Induce Neurite Outgrowth: The Involvement of SIRT1/Nrf2 Signaling Pathway and Teneurin 4 Transmembrane Protein

Frontiers in Pharmacology, 2021
Neurodegenerative diseases are linked to neuronal cell death and neurite outgrowth impairment that are often caused by oxidative stress. Natural products, which have neuroprotective against oxidative stress and neurite outgrowth inducing activity, could ...
Chatrawee Duangjan, Chatrawee Duangjan, Chatrawee Duangjan, Panthakarn Rangsinth, Panthakarn Rangsinth, Shaoxiong Zhang, Shaoxiong Zhang, Michael Wink, Tewin Tencomnao, Tewin Tencomnao, Tewin Tencomnao   +10 more
doaj   +1 more source

A Simple Distance Paper-Based Analytical Device for the Screening of Lead in Food Matrices

Biosensors, 2021
A simple and rapid distance paper-based analytical device (dPAD) for the detection of lead (Pb) in foods is proposed herein. The assay principle is based on competitive binding between carminic acid (CA) and polyethyleneimine (PEI) to Pb in a food sample.
Kasinee Katelakha, Vanida Nopponpunth, Watcharee Boonlue, Wanida Laiwattanapaisal   +3 more
doaj   +1 more source

Cleistocalyx nervosum var. paniala Berry Seed Protects against TNF-α-Stimulated Neuroinflammation by Inducing HO-1 and Suppressing NF-κB Mechanism in BV-2 Microglial Cells

Molecules, 2023
Sustained inflammatory responses have been implicated in various neurodegenerative diseases (NDDs). Cleistocalyx nervosum var. paniala (CN), an indigenous berry, has been reported to exhibit several health-beneficial properties. However, investigation of
Sakawrat Janpaijit, Chanin Sillapachaiyaporn, Atsadang Theerasri, Somsri Charoenkiatkul, Monruedee Sukprasansap, Tewin Tencomnao   +5 more
doaj   +1 more source

Neuroprotective Effects of Extracts from Tiger Milk Mushroom Lignosus rhinocerus Against Glutamate-Induced Toxicity in HT22 Hippocampal Neuronal Cells and Neurodegenerative Diseases in Caenorhabditis elegans

Biology, 2021
Despite the Tiger Milk Mushroom Lignosus rhinocerus (LR) having been used as a traditional medicine, little is known about the neuroprotective effects of LR extracts.
Parinee Kittimongkolsuk, Nattaporn Pattarachotanant, Siriporn Chuchawankul, Michael Wink, Tewin Tencomnao   +4 more
doaj   +1 more source

A computational pipeline combining machine learning and molecular simulations identifies repurposed PI3Kα inhibitors from FDA-approved drugs

Artificial Intelligence Chemistry
The computational repurposing of existing drugs has proven to be a fast-track strategy in the development of new cancer therapy. Nonetheless, integrated mechanistically grounded approaches are required for a more reliable in silico identification of new ...
Prince Danan Biniyam, Naomi Kayeri, Seth Junior Ayihi, Syed Arslan Haider, Hope Dzitorwoko, Kwabena Adu-Adjei, Michael Osei, Victoria Ohene-Adu, Portia Frimpong, Clifford Tignangnen Penajah, Silas Boakye Amissah, Nimra Mazhar, Cedric Dzidzor Kodjo Amengor   +12 more
doaj   +1 more source

Association of Drug-Metabolizing Enzyme and Transporter Gene Polymorphisms and Lipid-Lowering Response to Statins in Thai Patients with Dyslipidemia

Pharmacogenomics and Personalized Medicine, 2022
Natchaya Vanwong,1,2 Sayanit Tipnoppanon,1 Chalitpon Na Nakorn,3 Pornpen Srisawasdi,4 Punyanuch Rodcharoen,4 Sadeep Medhasi,5 Pajaree Chariyavilaskul,2,6,7 Sarawut Siwamogsatham,2,8,9 Yongkasem Vorasettakarnkij,2,9 Chonlaphat Sukasem10– 12 1Department of
Vanwong N, Tipnoppanon S, Na Nakorn C, Srisawasdi P, Rodcharoen P, Medhasi S, Chariyavilaskul P, Siwamogsatham S, Vorasettakarnkij Y, Sukasem C   +9 more
doaj  

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita, Norma Candelaria López Santiago, Claudia Maria García Cuellar, Karla Maldonado Silva, Nancy Reynoso Noverón, Leticia Hernández Cadena   +5 more
wiley   +1 more source

Antioxidant and Anti-Skin Aging Potential of Selected Thai Plants: In Vitro Evaluation and In Silico Target Prediction

Plants, 2022
The skin is the largest organ that performs a variety of the body’s essential functions. Impairment of skin structure and functions during the aging process might severely impact our health and well-being. Extensive evidence suggests that reactive oxygen
Kamonwan Chaikhong, Sawarin Chumpolphant, Panthakarn Rangsinth, Chanin Sillapachaiyaporn, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab   +6 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source