Results 191 to 200 of about 10,194 (239)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Vulvovaginal candidiasis: knowledge, practices and occurrence among pregnant women receiving antenatal care in a teaching hospital, Ghana. [PDF]

open access: yesFront Glob Womens Health
Edziah FS   +8 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Anticancer potential of fused heterocycles: structural insights and mechanistic advances. [PDF]

open access: yesAsian Biomed (Res Rev News)
Pandey A   +5 more
europepmc   +1 more source

UHPLC-QTOF-MS/MS-based metabolomic discovery of anticancer compounds in ethanolic extracts of Ficus hispida L. f. [PDF]

open access: yesPLoS One
Thammawithan S   +9 more
europepmc   +1 more source

Prescription Support Practice for Pharmacy Students: Pre-Post Educational Intervention Study.

open access: yesJMIR Med Educ
Aizawa F   +10 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy