E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Vulvovaginal candidiasis: knowledge, practices and occurrence among pregnant women receiving antenatal care in a teaching hospital, Ghana. [PDF]
Edziah FS +8 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Anticancer potential of fused heterocycles: structural insights and mechanistic advances. [PDF]
Pandey A +5 more
europepmc +1 more source
Decyl glucoside as a sustainable surfactant for cosmetic formulations: environmental stability under hardness, pH, and temperature variations. [PDF]
Abushuhel M +7 more
europepmc +1 more source
UHPLC-QTOF-MS/MS-based metabolomic discovery of anticancer compounds in ethanolic extracts of Ficus hispida L. f. [PDF]
Thammawithan S +9 more
europepmc +1 more source
Uptake of iron and folic acid supplements among pregnant women in Dar es Salaam, Tanzania. [PDF]
Koka CE, Bakari S, Njiro BJ, Sunguya BF.
europepmc +1 more source
Prescription Support Practice for Pharmacy Students: Pre-Post Educational Intervention Study.
Aizawa F +10 more
europepmc +1 more source
Correction to: Chromosome-level genome assembly of the common chiton, <i>Liolophura japonica</i> (Lischke, 1873). [PDF]
Hong Kong Biodiversity Genomics Consortium .
europepmc +1 more source

