Results 41 to 50 of about 6,653 (267)

Synergy effects of copper ion in doxorubicin-based chelate prodrug for cancer chemo-chemodynamic combination therapy

Drug Delivery, 2023
Doxorubicin (DOX) is a commonly studied chemotherapeutic agent for the treatment of solid tumors, but the severe side effects limit its clinical application.
Wen Zhang, Peng Zhang, Xiaopeng Xu, Minghui Li, Shasha Wang, Hongjie Mu, Kaoxiang Sun   +6 more
doaj   +1 more source

Magnetic Silica Nanosystems With NIR-Responsive and Redox Reaction Capacity for Drug Delivery and Tumor Therapy

Frontiers in Chemistry, 2020
In recent years, more and more researches have focused on tumor photothermal therapy and chemodynamic therapy. In this study, we prepared a multifunctional nanomaterial with potential applications in the above area.
Chengzheng Jia, Hang Wu, Keyi Luo, Weiju Hao, Shige Wang, Mingxian Huang   +5 more
doaj   +1 more source

Mn doped Prussian blue nanoparticles for T1/T2 MR imaging, PA imaging and Fenton reaction enhanced mild temperature photothermal therapy of tumor

Journal of Nanobiotechnology, 2022
Background Combining the multimodal imaging and synergistic treatment in one platform can enhance the therapeutic efficacy and diagnosis accuracy. Results In this contribution, innovative Mn-doped Prussian blue nanoparticles (MnPB NPs) were prepared via ...
Quan Tao, Genghan He, Sheng Ye, Di Zhang, Zhide Zhang, Li Qi, Ruiyuan Liu   +6 more
doaj   +1 more source

A bimetallic nanocatalyst for light-free oxygen sensitization therapy

Cell Reports Physical Science, 2021
Summary: Singlet oxygen (1O2) is extensively employed by reactive oxygen species (ROS)-based cancer therapies, such as photodynamic therapy (PDT) and chemodynamic therapy (CDT).
Xia Guo, Hongwei Liao, Jiaming Tian, Chuang Yang, Fan Xia, Wenshi Liang, Nan Wang, Pin Li, Bo Zhang, Linji Gong, Xi Hu, Liang Zhang, Fangyuan Li, Daishun Ling   +13 more
doaj   +1 more source

Alginate-Based Micro- and Nanosystems for Targeted Cancer Therapy

Marine Drugs, 2022
Alginates have been widely explored due to their salient advantages of hydrophilicity, biocompatibility, mucoadhesive features, bioavailability, environmentally-benign properties, and cost-effectiveness.
Siavash Iravani, Rajender S. Varma
doaj   +1 more source

Self‐Supply of O2 and H2O2 by a Nanocatalytic Medicine to Enhance Combined Chemo/Chemodynamic Therapy

Advanced Science, 2019
Combined chemo/chemodynamic therapy is a promising strategy to achieve an improved anticancer effect. However, the hypoxic microenvironment and limited amount of H2O2 in most solid tumors severely restrict the efficacy of this treatment.
Shutao Gao, Yan Jin, Kun Ge, Zhenhua Li, Huifang Liu, Xinyue Dai, Yinghua Zhang, Shizhu Chen, Xingjie Liang, Jinchao Zhang   +9 more
doaj   +1 more source

Multifunctional drug delivery nanoparticles based on MIL-100 (Fe) for photoacoustic imaging-guided synergistic chemodynamic/chemo/photothermal breast cancer therapy

Materials & Design, 2022
Compared with visceral cancers, breast cancer is epidermal and can be efficiently eliminated by photoacoustic imaging (PAI)-guided cancer therapy. In this study, we developed multifunctional nanoparticles (DMTH NPs) by loading doxorubicin (DOX) into MIL ...
Zhiming Hu, Caina Xu, Yonghao Liang, Taiyuan Liu, Huayu Tian, Yingchao Zhang   +5 more
doaj   +1 more source

Tumor microenvironment responsive metal nanoparticles in cancer immunotherapy [PDF]

, 2023
Malignant tumors have a unique tumor microenvironment (TME), which includes mild acidity, hypoxia, overexpressed reactive oxygen species (ROS), and high glutathione (GSH) levels, among others. Recently, TME regulation approaches have attracted widespread
Lijuan Zhang, Lu Chen, Rou Yang, Xi Zheng, Yiling Wang, Yong Yang, Yuxuan Zhu   +6 more
core   +1 more source

Sequential Tumor Microenvironment Reprogramming by Nanoplatform Potentiates Sonodynamic-Chemodynamic Therapy and Immune Checkpoint Blockade in Breast Cancer. [PDF]

Adv Sci (Weinh)
Yu Y, Song Z, Zhu A, Li J, Fan R, Xiao B.   +5 more
europepmc   +2 more sources

Metal ion-zeolite nanomaterials for chemodynamic therapy [PDF]

, 2021
A new therapeutic approach called chemodynamic therapy (CDT), which can be defined as specific OH generation in cancer cells via Fenton reactions, was recently proposed.1 The advantages of CDT can be ascribed to the higher specificity, no external field ...
Almeida Aguiar, Cristina, Baltazar, F., Bertão, A. R., Carvalho, V. M. C, Ferreira, S. D. C., Fonseca, António, Neves, Isabel C., Oliveira, R. D., Rodrigues, F. C.   +8 more
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