Results 181 to 190 of about 468,477 (308)

Age-associated chemokine receptor expression profiles in human peripheral blood monocyte subsets predict cardiovascular disease risk. [PDF]

Front Immunol
Komaravolu RK, Chatterjee N, Kumar S, Allen JL, Durant C, Wu R, Valentin-Guillama G, McSkimming C, Drago F, Taylor AM, Miller YI, Ley K, McNamara CA, Alimadadi A, Hedrick CC.   +14 more
europepmc   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma. [PDF]

Nat Cancer
Czernilofsky F, Mathioudaki A, Jopp-Saile L, Lutz R, Vonficht D, Wang X, Schniederjohann C, Voehringer H, Roider T, Baertsch MA, Rodemer C, Löffler-Wirth H, Grau M, Fitzgerald D, Mammen J, Kosla J, Liebers N, Bruch PM, Ordoñez-Rueda D, Brobeil A, Mechtersheimer G, Pabst C, Müller-Tidow C, Trumpp A, Seifert M, Neumann F, Heikenwälder M, Benes V, Huber W, Distler J, Lenz G, Binder H, Siebert R, Nolan GP, Gerstung M, Zaugg JB, Hübschmann D, Haas S, Dietrich S.   +38 more
europepmc   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Viral Chemokine Receptors

Frontiers in Immunology, 2015
Philip eMurphy
doaj   +1 more source

Restriction of HSV-1 replication by Pistacia vera L. extracts reveals a promising strategy for regulating virus-mediated chemokine response in monocytic cells. [PDF]

Sci Rep
Pennisi R, Costa M, Tamburello MP, Trischitta P, Mandalari G, Sciortino MT.   +5 more
europepmc   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Corrigendum: Identification of differentially expressed hub genes associated with immune cell recruitment in claudin-low breast cancer

Frontiers in Oncology
Yange Wang, He Shi, Yulu Zhang, Qian Zeng, Tingmei Chen, Chengsen Chai   +5 more
doaj   +1 more source

Serum Levels of Selected Chemokines in Patients with Systemic Lupus Erythematosus Correlate with Disease Activity and Clinical Features: Results from a Single-Center Observational Study. [PDF]

Biomedicines
Dziedzic R, Siwiec-Koźlik A, Koźlik-Siwiec P, Węglarczyk K, Siedlar M, Korkosz M, Kosałka-Węgiel J.   +6 more
europepmc   +1 more source