Results 91 to 100 of about 16,804 (217)
Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity [PDF]
, 2017 Indexación: Web of Science; Scopus.The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly worldwide.
Alexis M. Kalergis +9 more
core +2 more sources
Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics
Aggregate, Volume 7, Issue 3, March 2026.Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang +5 more
wiley +1 more source
Causal Associations of Cardiovascular Proteins and Diabetic Nephropathy Revealed by Mediation and Phenome-Wide Mendelian Randomization [PDF]
Endocrinology and MetabolismCardiovascular factors play a critical role in the progression of diabetic nephropathy (DN). This study utilized Mendelian randomization analysis to explore the causal relationships among cardiovascular proteins, risk factors, and DN.
Lei Chen +4 more
doaj +1 more source
Microglia modulate hippocampal neural precursor activity in response to exercise and aging [PDF]
, 2012 Exercise has been shown to positively augment adult hippocampal neurogenesis; however, the cellular and molecular pathways mediating this effect remain largely unknown. Previous studies have suggested that microglia may have the ability to differentially
Bartlett, Perry F. +4 more
core +2 more sources
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Emerging evidence highlights the central role of peripheral immune–metabolic regulation in the pathogenesis of Alzheimer's disease and related dementias (ADRD). Among peripheral organs, the spleen has gained increasing attention as a critical immune–metabolic hub linking systemic homeostasis to central neurodegeneration.
Jingsi Yan +7 more
wiley +1 more source
Free water changes and their correlations with multimodal biomarkers in frontotemporal dementia
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION The alterations of free water (FW) in behavioral variant frontotemporal dementia (bvFTD) and its clinical correlations remain unclear. METHODS FW levels in the whole brain and specific white matter fiber tract was evaluated in 112 bvFTD patients and 103 normal controls.
Min Chu +13 more
wiley +1 more source
Basal adenosine modulates the functional properties of AMPA receptors in mouse hippocampal neurons through the activation of A1R A2AR and A3R [PDF]
, 2015 Adenosine is a widespread neuromodulator within the CNS and its extracellular level is increased during hypoxia or intense synaptic activity, modulating pre- and postsynaptic sites.
BERTOLLINI, Cristina +7 more
core +1 more source
Cancer Medicine, Volume 15, Issue 3, March 2026.ABSTRACT Background Conventional treatment strategies and immunotherapy yield low response rates in head and neck squamous cell carcinoma (HNSCC). This study aimed to explore the potential of immunosuppressive receptor leukocyte immunoglobulin‐like receptor subfamily B member 1 (LILRB1) for developing effective immunotherapies for HNSCC.
Shuai Chen +11 more
wiley +1 more source
Open Access Rheumatology: Research and Reviews, 2011 Michihito Sato, Kumiko Ohtsuka, Ryo Takahashi, Kuninobu Wakabayashi, Tsuyoshi Odai, Takeo Isozaki, Nobuyuki Yajima, Yusuke Miwa, Tsuyoshi KasamaDivision of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, JapanObjective ...
Michihito Sato +3 more
doaj
CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice
Molecular Metabolism, 2019 Objective: Atherosclerosis is a major cause of cardiovascular disease. Monocyte-endothelial cell interactions are partly mediated by expression of monocyte CX3CR1 and endothelial cell fractalkine (CX3CL1). Interrupting the interaction between this ligand–
Matthew Riopel +18 more
doaj +1 more source