Results 111 to 120 of about 16,804 (217)
Primary Phagocytosis of Neurons by Inflamed Microglia: Potential Roles in Neurodegeneration [PDF]
, 2012 Microglial phagocytosis of dead or dying neurons can be beneficial by preventing secondary necrosis and release of pro-inflammatory intracellular components.
Jonas J. Neher +2 more
core +2 more sources
Murine cytomegalovirus (CMV) M33 and human CMV US28 receptors exhibit similar constitutive signaling activities [PDF]
, 2002 Cellular infection by cytomegalovirus (CMV) is associated with very early G-protein-mediated signal transduction and reprogramming of gene expression. Here we investigated the involvement of human CMV (HCMV)-encoded US27, US28, and UL33 receptors as well
Waldhoer, Maria +3 more
core +1 more source
Oncology Reports, 2012 Meningiomas are common slowly growing benign tumors, however, anaplastic meningiomas have an aggressive biological and clinical behavior associated with high rates of recurrence and unfavorable prognosis. Since the molecular mechanisms involved in progression of meningiomas are not yet fully understood and recent
Gu, Li +4 more
openaire +3 more sources
Shear Stress Counteracts Endothelial CX3CL1 Induction and Monocytic Cell Adhesion
Mediators of Inflammation, 2017 Flow conditions critically regulate endothelial cell functions in the vasculature. Reduced shear stress resulting from disturbed blood flow can drive the development of vascular inflammatory lesions.
Aaron Babendreyer +4 more
doaj +1 more source
Frontiers in Pharmacology, 2017 An increasing number of studies indicate that the chemokine system may be the third major communication system of the brain. Therefore, the role of the chemokine system in the development of brain disorders, including depression, has been recently ...
Ewa Trojan +6 more
doaj +1 more source
Journal of General Virology, 2013 Human cytomegalovirus (HCMV)-encoded G protein-coupled-receptor US28 is believed to participate in virus dissemination through modulation of cell migration and immune evasion. US28 binds different CC chemokines and the CX3C chemokine CX3CL1. Membrane-anchored CX3CL1 is expressed by immune-activated endothelial cells, causing redirection of CX3CR1 ...
Gertrud M, Hjortø +4 more
openaire +2 more sources
Recruitment of CD16+ monocytes into synovial tissues is mediated by fractalkine and CX3CR1 in rheumatoid arthritis patients [PDF]
, 2007 CD16+ monocytes, identified as a minor population of monocytes in human peripheral blood, have been implicated in several inflammatory diseases, including rheumatoid arthritis (RA).
Kawashima, Masanori +6 more
core +1 more source
CXCL16/CXCR6 axis drives microglia/macrophages phenotype in physiological conditions and plays a crucial role in glioma [PDF]
, 2018 Microglia are patrolling cells that sense changes in the brain microenvironment and respond acquiring distinct phenotypes that can be either beneficial or detrimental for brain homeostasis.
Antonangeli, Fabrizio +6 more
core +1 more source
Centripetal migration and prolonged retention of microglia promotes spinal cord injury repair
Journal of NeuroinflammationBackground Recent studies have confirmed the critical role of neonatal microglia in wound healing and axonal regeneration following spinal cord injury (SCI).
Jianan Ye +15 more
doaj +1 more source
Mediators of Inflammation, 2014 Fractalkine/CX3CL1, the only member of the CX3C chemokine family, exists as a membrane-anchored molecule as well as in soluble form, each mediating different biological activities. It is constitutively expressed in many hematopoietic and nonhematopoietic
Elisa Ferretti +2 more
doaj +1 more source