Results 121 to 130 of about 16,804 (217)

Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

Molecular Metabolism, 2014
Objective: We have previously shown the existence of a muscle–pancreas intercommunication axis in which CX3CL1 (fractalkine), a CX3C chemokine produced by skeletal muscle cells, could be implicated.
Sabine Rutti, Caroline Arous, Domitille Schvartz, Katharina Timper, Jean-Charles Sanchez, Emmanouil Dermitzakis, Marc Y. Donath, Philippe A. Halban, Karim Bouzakri   +8 more
doaj   +1 more source

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama, Bruce C. Richardson, Dipak Patel, Faith M. Strickland, Sushma Yarlagadda   +4 more
core   +1 more source

Die Rolle der Chemokine CXCL9 und CX3CL1 bei der Immunantwort im Ovarialkarzinom [PDF]

, 2022
Die vorliegende Studie fokussierte sich auf das „high-grade“ seröse Ovarialkarzinom und adressierte die Rolle der Chemokine CXCL9 und CX3CL1 in der Immunantwort. In murinen Studien konnte durch eine CXCL9-Überexpression die Anzahl von tumor-infiltrierenden Lymphozyten soweit erhöht werden, dass sich in Kombination mit einer anti-PD-L1 Immuncheckpoint ...
openaire  

Editorial research topic "Chemokines and chemokine receptors in brain homeostasis" [PDF]

, 2015
Ransohoff, Richard M, Trettel, Flavia
core   +2 more sources

Synergistic induction of CX3CL1 by TNF alpha and IFN gamma in osteoblasts from rheumatoid arthritis: involvement of NF-kappa B and STAT-1 signaling pathways

Journal of Inflammation Research, 2008
Takeo Isozaki, Tsuyoshi Kasama, Ryo Takahashi, Tsuyoshi Odai, Kuninobu Wakabayashi, Hirohito Kanemitsu, Kyoko Nohtomi, Hiroko T Takeuchi, Satoshi Matsukura, Masakazu TezukaDivision of Rheumatology, Department of Internal Medicine, Showa University School
Kuninobu Wakabayashi, Tsuyoshi Odai, Ryo Takahashi, Tsuyoshi Kasama, Takeo Isozaki, et al   +5 more
doaj  

Double-faced CX3CL1 enhances lymphangiogenesis-dependent metastasis in an aggressive subclone of oral squamous cell carcinoma

JCI Insight
Because cancer cells have a genetically unstable nature, they give rise to genetically different variant subclones inside a single tumor. Understanding cancer heterogeneity and subclone characteristics is crucial for developing more efficacious therapies.
Htoo Shwe Eain, Hotaka Kawai, Masaaki Nakayama, May Wathone Oo, Toshiaki Ohara, Yoko Fukuhara, Kiyofumi Takabatake, Quisheng Shan, Yamin Soe, Kisho Ono, Keisuke Nakano, Nobuyoshi Mizukawa, Seiji Iida, Hitoshi Nagatsuka   +13 more
doaj   +1 more source

CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation via NSUN5-mediated m5C modification

Scientific Reports
Bone homeostasis refers to a dynamic equilibrium maintained between osteogenesis and osteoclastic bone resorption within the skeletal system. CX3CL1 (Fractalkine) is a chemokine that plays a significant regulatory role in bone homeostasis.
Zhibin Deng, Wei Zhong
doaj   +1 more source

Polyphyllin VII promotes hepatic stellate cell ferroptosis via the HIC1/CX3CL1/GPX4 axis

Journal of Pharmaceutical Analysis
Ferroptosis has been shown to mediate the development of fibrosis. Polyphyllin VII (PP7), a bioactive component of Paris polyphylla, exhibits potent anti-inflammatory activity and can significantly alleviate liver fibrosis.
Feng Jiang, Xinmiao Li, Mengyuan Li, Weizhi Zhang, Yifei Li, Lifan Lin, Lufan He, Jianjian Zheng   +7 more
doaj   +1 more source

A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation. [PDF]

, 2020
BackgroundInteractions between neurons, astrocytes, and microglia critically influence neuroinflammatory responses to insult in the central nervous system.
Goshi, Noah, Lein, Pamela J, Morgan, Rhianna K, Seker, Erkin   +3 more
core  

Functional Adhesiveness of the CX3CL1 Chemokine Requires Its Aggregation [PDF]

Journal of Biological Chemistry, 2008
Patricia Hermand, Frédéric Pincet, Stéphanie Carvalho, Hervé Ansanay, Eric Trinquet, Mehdi Daoudi, Christophe Combadière, Philippe Deterre   +7 more
openaire   +1 more source