Results 71 to 80 of about 16,804 (217)
iNew Medicine, EarlyView.This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source
Frontiers in ImmunologySystemic lupus erythematosus (SLE) is a systemic chronic disease initiated by an abnormal immune response to self and can affect multiple organs. SLE is characterized by the production of autoantibodies and the deposition of immune complexes.
Rana A. Estaleen +2 more
doaj +1 more source
Role of CX3CL1/CX3CR1 Signaling Axis Activity in Osteoporosis
Mediators of Inflammation, 2019 Osteoporosis is a civilization disease which is still challenging for contemporary medicine in terms of treatment and prophylaxis. It results from excessive activation of the osteoclastic cell line and immune cells like macrophages and lymphocytes.
Piotr Wojdasiewicz +4 more
doaj +1 more source
Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators [PDF]
, 2013 BACKGROUND: Noradrenaline (NA) is known to limit neuroinflammation. However, the previously described induction by NA of a chemokine involved in the progression of immune/inflammatory processes, such as chemokine (C-C motif) ligand 2 (CCL2)/monocyte ...
Ara E Hinojosa +4 more
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Scientific ReportsWe evaluated chemokine expression and its correlation with disease activity in patients with microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA) (MPA/GPA).
Ji Eun Lee +3 more
doaj +1 more source
Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor [PDF]
, 2015 Chemokines are small proteins that function as immune modulators through activation of chemokine G protein–coupled receptors (GPCRs). Several viruses also encode chemokines and chemokine receptors to subvert the host immune response.
Angelini, Alessandro +10 more
core +1 more source
Movement Disorders, EarlyView.Abstract Background Emerging evidence implicates neuroinflammation in progressive supranuclear palsy (PSP) pathophysiology, with elevated cyto‐chemokines suggesting natural killer (NK) cell involvement. Methods We characterized peripheral NK in PSP (N = 11) versus Parkinson's disease (PD, N = 10) and healthy controls (HC, N = 8) at both ...
Marina Picillo +11 more
wiley +1 more source
MicroRNA-155 regulates monocyte chemokine and chemokine receptor expression in Rheumatoid Arthritis [PDF]
, 2016 Objectives: To test the hypothesis that miR-155 regulates monocyte migratory potential via modulation of chemokine and chemokine receptor expression in rheumatoid arthritis (RA); and thereby is associated with disease activity.
Elmesmari, Aziza +8 more
core +1 more source
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Background and Hypothesis Deficits in processing speed (PS) and psychomotor speed (PMS) are core cognitive impairments in schizophrenia spectrum disorders, including first‐episode psychosis (FEP). Neuroinflammation has been proposed as a potential contributor to these deficits.
Ángel Yorca‐Ruiz +8 more
wiley +1 more source