Results 101 to 110 of about 763,282 (296)
Haematologica, 2006 BACKGROUND AND OBJECTIVES: The capacity of multiple myeloma (MM) cells to home to and reside in the bone marrow implies that they must be equipped with appropriate adhesion molecules and chemokine receptors to allow transendothelial migration.
I Van de Broek +6 more
doaj
The Role of Chemokines in Breast Cancer Pathology and Its Possible Use as Therapeutic Targets
Journal of Immunology Research, 2014 Chemokines are small proteins that primarily regulate the traffic of leukocytes under homeostatic conditions and during specific immune responses. The chemokine-chemokine receptor system comprises almost 50 chemokines and approximately 20 chemokine ...
M. Isabel Palacios-Arreola +5 more
doaj +1 more source
Chemokines, chemokine receptors and the gastrointestinal system
World Journal of Gastroenterology, 2013 The biological properties of tumor cells are known to be regulated by a multitude of cytokines and growth factors, which include epidermal growth factor receptor agonists and members of the transforming growth factor β family. Furthermore, the recent explosion of research in the field of chemokine function as mediators of tumor progression has led to ...
Hiroshi, Miyazaki +2 more
openaire +2 more sources
Atypical chemokine receptors : from silence to sound [PDF]
, 2013 ACRs (atypical chemokine receptors) were initially referred to as 'silent' receptors on the basis of a lack of signalling and functional activities that are typically observed with conventional chemokine receptors.
M. Locati +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão +5 more
wiley +1 more source
Hetero‐Oligomerization of Chemokine Receptors
, 2009 Although traditionally assumed to be monomeric signaling units, G[hyphen (true graphic)]protein-coupled receptors (GPCRs) have been shown to exist as dimers/oligomers.
Graeme Milligan +3 more
core +1 more source
Information Transmission Strategies for Self‐Organized Robotic Aggregation
Advanced Robotics Research, EarlyView.In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng +5 more
wiley +1 more source
Biased and G protein-independent signaling of chemokine receptors
Frontiers in Immunology, 2014 Biased signaling or functional selectivity occurs when a 7TM receptor preferentially activates one of several available pathways. It can be divided into three distinct forms: ligand bias, receptor bias, and tissue or cell bias, where it is mediated by ...
Anne eSteen +3 more
doaj +1 more source
Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic
Advanced Robotics Research, EarlyView.Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang +5 more
wiley +1 more source
Frontiers in AllergyAtopic dermatitis (AD) is a chronic inflammatory skin disease that commonly causes eczema accompanied by severe itching on pathological skin lesions. Although the pathological mechanisms are not fully understood, epidermal barrier dysfunction and immune ...
Rio Tsukamoto +6 more
doaj +1 more source