Results 141 to 150 of about 174,841 (260)

Gene Expression Changes in Cytokine and Chemokine Receptors in Association with Melanoma Liver Metastasis. [PDF]

Int J Mol Sci, 2023
Koroknai V, Szász I, Balázs M.
europepmc   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source

Chemokine receptors in vascular biology: a review of current evidence, implications, and therapeutic targets for hypertension. [PDF]

Clin Sci (Lond)
Oliveira de Moraes LH, Beling T, Felix Pimenta G, Bruder-Nascimento T.   +3 more
europepmc   +1 more source

Comprehensive analysis and immune landscape of chemokines- and chemokine receptors-based signature in hepatocellular carcinoma. [PDF]

Front Immunol, 2023
Zhang Z, Mao M, Wang F, Zhang Y, Shi J, Chang L, Wu X, Zhang Z, Xu P, Lu S.   +9 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Circulating fibroblasts and neutrophils co-expressing CDH11⁺ and chemokine receptors in rheumatoid and psoriatic arthritis: a shared mechanism of 'arthritis spreading'? [PDF]

Front Immunol
Kyriakidi M, Vetsika EK, Fragoulis GE, Sakkou M, Verrou KM, Mourikis A, Vlachogiannis NI, Tektonidou MG, Sfikakis PP.   +8 more
europepmc   +1 more source

CD28 and chemokine receptors: Signalling amplifiers at the immunological synapse. [PDF]

Front Immunol, 2022
Molon B, Liboni C, Viola A.
europepmc   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source

Chemokine Receptors in Peripheral Blood Mononuclear Cells as Predictive Biomarkers for Immunotherapy Efficacy in Non-Small Cell Lung Cancer. [PDF]

Curr Oncol
Galera P, Iglesias-Beiroa A, Hernández-Marín B, Bañón D, Arangoa T, Castillo L, Álvarez-Maldonado M, Gil-Olarte C, Borregón R, Iribarren M, Colomer R, Rogado J.   +11 more
europepmc   +1 more source

Efficient Redirection of NK Cells by Genetic Modification with Chemokine Receptors CCR4 and CCR2B. [PDF]

Int J Mol Sci, 2023
Feigl FF, Stahringer A, Peindl M, Dandekar G, Koehl U, Fricke S, Schmiedel D.   +6 more
europepmc   +1 more source