Results 221 to 230 of about 174,841 (260)
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Chemokine Receptors and Chemokines in HIV Infection
Journal of Clinical Immunology, 1998Suppression of HIV by chemokines represents a special case in virology and immunology where soluble molecules other than antibodies inhibit infection by a specific virus. The basis for this inhibition is that HIV has evolved to use certain chemokine receptors as "coreceptors" for entry into host cells.
GARZINO DEMO, ALFREDO +2 more
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Chemokines and Chemokine Receptors
2001The recruitment of cells to sites of inflammation is an essential component of the host inflammatory response. Cell recruitment relies on the coordinated action of cell activation, cell adhesion, chemoattraction, and transmigration across the endothelial barrier.
Andrew D. Luster, James MacLean
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Chemokines and chemokine receptors in infectious diseases
Immunology & Cell Biology, 1999Today, 10 years after the discovery of IL‐8, chemokines (chemotactic cytokines) are seen as the stimuli that largely control leucocyte migration. Chemokines are low molecular weight chemoattractant cytokines secreted by a variety of cells, including leucocytes, epithelial cells, endothelial cells, fibroblasts and numerous other cell types.
S, Mahalingam, G, Karupiah
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Chemokines and chemokine receptors
2009There is a structural and a functional classification of chemokines. The former includes four groups: CXC, CC, C and CX3C chemokines. There is a redundancy and binding promiscuity between chemokine receptors and their ligands. Recently, a functional classification distinguishing between inflammatory and homeostatic chemokines has been introduced ...
Zoltán Szekanecz, Alisa E. Koch
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Chemokines and chemokine receptors in leukocyte trafficking
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2002Chemokines regulate inflammation, leukocyte trafficking, and immune cell differentiation. The role of chemokines in homing of naive T lymphocytes to secondary lymphatic organs is probably the best understood of these processes, and information on chemokines in inflammation, asthma, and neurological diseases is rapidly increasing. Over the past 15 years,
Timothy S, Olson, Klaus, Ley
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Recent Advances in Chemokines and Chemokine Receptors
Critical Reviews™ in Immunology, 1999Chemokines are a superfamily of small cytokine-like molecules which have been described primarily on the basis of their ability to mediate the migration of verious cell types, particularly those of lymphoid origin. The receptors for these molecules are all seven-transmembrane domain G protein-coupled receptors that have historically been excellent ...
A, Zlotnik, J, Morales, J A, Hedrick
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Chemokines and chemokine receptors in inflammation of the CNS
Expert Review of Clinical Immunology, 2005Chemokines are small chemotactic cytokines involved in numerous biologic and pathologic processes. They are important mediators of leukocyte trafficking, development of inflammation, tumor metastasis and immune cell differentiation. Inflammation in the CNS develops in a unique manner that is partially due to the existence of the blood-brain barrier ...
Andrzej, Glabinski +2 more
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Characterization of Chemokine Receptors
Current Protocols in Pharmacology, 2001AbstractThis unit describes the procedures for measuring binding of a radiolabeled chemokine to chemokine receptors in cells or cell membranes. The whole‐cell binding assay can be used for both purified leukocytes as well as transfected cell lines expressing chemokine receptors. Two basic protocols are described.
A, Scheer, A E, Proudfoot
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Chemokines and Chemokine Receptors in the Development of NAFLD
2018Chemokines are chemo-attractants for leukocyte trafficking, growth, and activation in injured and inflammatory tissues. The chemokine system is comprised of 50 chemokine ligands and 20 cognate chemokine receptors. In the context of liver diseases, leukocytes, hepatocytes, hepatic stellate cells, endothelial cells, and vascular smooth muscle cells are ...
Yoon-Seok, Roh, Ekihiro, Seki
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Chemokine/Chemokine Receptor Nomenclature
Journal of Interferon & Cytokine Research, 2002Kevin, Bacon +18 more
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