Results 101 to 110 of about 19,998 (230)

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Anti-mycobacterial treatment reduces high plasma levels of CXC-chemokines detected in active tuberculosis by cytometric bead array

Memorias do Instituto Oswaldo Cruz, 2009
Chemokines recruit and activate leukocytes, assisting granuloma formation. Herein, we evaluated plasma chemokines in patients with active tuberculosis (ATB) and after completing treatment (TTB) and compared them to BCG-vaccinated healthy controls (HC ...
Caroline de Souza Almeida, Clarice Abramo, Caio César de Souza Alves, Luciano Mazzoccoli, Ana Paula Ferreira, Henrique Couto Teixeira   +5 more
doaj   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Corneal and Conjunctival Fibroblasts Are Major Sources of Eosinophil-Recruiting Chemokines

Allergology International, 2009
Background: Differential expression of chemokine genes were investigated in various types of ocular surface cells. Methods: Primary cultures of human corneal epithelial cells (n = 3), corneal fibroblasts (n = 2), conjunctival epithelial cells (n = 2) and
Kazumi Fukagawa, Naoko Okada, Hiroshi Fujishima, Toshiharu Nakajima, Yoji Takano, Mari Tanaka, Murat Dogru, Yoshiyuki Satake, Kazuo Tsubota, Hirohisa Saito   +9 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, Volume 16, Issue 7, Page 1244-1258, July 2026.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes

, 2012
Cytokines play an important role in ischemic injury and repair. However, little is known about their prognostic value in cardiovascular disease. The aim of this study was to investigate the prognostic importance of chemokines CCL3/MIP-1α, CCL5/RANTES and
van Dieijen-Visser, Marja P., Brenda W. C. Bongaerts (134222), Erik A. L. Biessen (132311), Michael Weber (134225), Brenda W C Bongaerts, Stefanie Dimmeler (134234), van Berkel, Theo J. C., Patty J. Nelemans (134239), Michael Weber, Mat Rousch (134231), Kitty B. J. M. Cleutjens (134238), Jager, Saskia C. A. de, Dieijen-Visser, Marja P. van, Cleutjens, Kitty B. J. M., Nelemans, Patty J., Biessen, Erik A. L., Mat Rousch, Bongaerts, Brenda W. C., Saskia C A de Jager, Marja P. van Dieijen-Visser (134236), Weber, Michael, Marja P van Dieijen-Visser, Adriaan O. Kraaijeveld (134229), Berkel, Theo J. C. van, Rousch, Mat, Biessen, Erik A. L.; id_orcid, de Jager, Saskia C. A., Theo J C van Berkel, Adriaan O Kraaijeveld, Stefanie Dimmeler, Dimmeler, Stefanie, Kraaijeveld, Adriaan O., Theo J. C. van Berkel (132307), Kitty B J M Cleutjens, Erik A L Biessen, Patty J Nelemans, Saskia C. A. de Jager (134219)   +36 more
core   +1 more source

Transcriptomal signatures of vaccine adjuvants and accessory immunostimulation of sentinel cells by toll-like receptor 2/6 agonists

Human Vaccines & Immunotherapeutics, 2018
An important component of vaccine development is the identification of safe and effective adjuvants. We sought to identify transcriptomal signatures of innate immune stimulating molecules using next-generation RNA sequencing with the goal of being able ...
Alex C. D. Salyer, Sunil A. David
doaj   +1 more source

Genomic organization, annotation, and ligand-receptor inferences of chicken chemokines and chemokine receptor genes based on comparative genomics

BMC Genomics, 2005
Background Chemokines and their receptors play important roles in host defense, organogenesis, hematopoiesis, and neuronal communication. Forty-two chemokines and 19 cognate receptors have been found in the human genome.
Sze Sing-Hoi, Yilmaz Ahmet, Adelson David L, Wang Jixin, Jin Yuan, Zhu James J   +5 more
doaj   +1 more source

ELR positive CXCL chemokines are highly expressed in an animal model of ulcerative colitis

Journal of Inflammation Research, 2019
Mohammad Amin Boshagh,1,2 Poorya Foroutan,1,2 Mohammad Raman Moloudi,3 Shohreh Fakhari,1 Parisa Malakouti,1 Bahram Nikkhoo,1 Ali Jalili1,21Cancer and Immunology Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran; 2Department of ...
Boshagh MA, Foroutan P, Moloudi MR, Fakhari S, Malakouti P, Nikkhoo B, Jalili A   +6 more
doaj  

Inflammatory signatures in the spectrum of myeloid diseases

HemaSphere, Volume 10, Issue 7, July 2026.
Abstract Dysregulated innate immunity contributes to clonal cytopenias and myeloid neoplasms, but its extent across disease stages and clinical relevance remain incompletely defined. We analyzed plasma ASC/NLRP3 double‐positive (DP) specks, ASC single‐positive (SP) specks, and 45 cytokines in 223 patients with idiopathic cytopenias of undetermined ...
Alice Ibbotson, Simon Crouch, Jacqueline Ferrari, Thomas Young, Ann W. Morgan, Anna Gallì, Sara Pozzi, Martina Sarchi, Virginia Camilotto, Martina Boldini, Chiara Elena, Luca Malcovati, Sinisa Savic   +12 more
wiley   +1 more source