Results 121 to 130 of about 19,998 (230)

Ras regulates alveolar macrophage formation of CXC chemokines and neutrophil activation in streptococcal M1 protein-induced lung injury

, 2014
Streptococcal toxic shock syndrome (STSS) is associated with a high mortality rate. The M1 serotype of Streptococcus pyogenes is most frequently associated with STSS. Herein, we examined the role of Ras signaling in M1 protein-induced lung injury.
Rahman, Milladur,, Thorlacius, Henrik,, Zhang, Songen,, Lund University., Herwald, Heiko,, Hwaiz, Rundk,   +5 more
core   +2 more sources

Rat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines

, 2007
We analyzed the ability of two rat coronavirus (RCoV) strains, sialodacryoadenitis virus (SDAV) and Parker's RCoV (RCoV-P), to infect rat alveolar type I cells and induce chemokine expression.
Miura, Tanya A., Holmes, Kathryn V., Tanya A. Miura, Kathryn V. Holmes, Jieru Wang, Robert J. Mason, Wang, Jieru, Mason, Robert J.   +7 more
core   +1 more source

From monoclonal to polyfunctional immunotherapy: Reprogramming CAR‐T‐cell therapy with oncolytic viruses in B‐cell malignancies

HemaSphere, Volume 10, Issue 7, July 2026.
Eduard Achim, Guy Ungerechts, Ciprian Tomuleasa, Sabrina Friedel, Michael Hudecek, Cecilia Cristea, Mihaela Tertis, Hermann Einsele   +7 more
wiley   +1 more source

CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosis.

, 2012
Recent studies from our group suggest that extracellular matrix (ECM) deposition and fibrosis characterize the peri-urethral prostate tissues of some men suffering from Lower Urinary Tract Symptoms (LUTS) and that fibrosis may be a contributing factor to
Mehrnaz Gharaee-Kermani (118877), Sathish Kasina (118881), Jill A Macoska, Dafydd Thomas (118889), Dafydd Thomas, Bethany B. Moore (118885), Rohit Mehra (118892), Jill A. Macoska (118895), Rohit Mehra, Mehrnaz Gharaee-Kermani, Sathish Kasina, Bethany B Moore   +11 more
core   +1 more source

CXC chemokine receptor type 5 may induce trophoblast dysfunction and participate in the processes of unexplained missed abortion, wherein p-ERK and interleukin-6 may be involved

Heliyon
Chemokines regulate the trophoblast dysfunction involved in the occurrence and development of pathological pregnancy, including missed abortions. In particular, CXC chemokine receptor type 5 mediates cell proliferation, migration, and inflammation ...
Yanan Zhi, Pingping Zhang, Yan Luo, Yanmei Sun, Juan Li, Mingming Zhang, Yali Li   +6 more
doaj   +1 more source

CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood-brain barrier breakdown.

, 1998
Children are at greater risk than adults of permanent brain damage and mortality following head injury or infection [1-5]. Rodent models have demonstrated a 'window of susceptibility' in young animals during which the brain parenchyma is at greater risk ...
Anthony, Daniel, Clements, John, Wells, G, Clements, J, Fearn, S, Fearn, Sara, Dempster, Robert, Perry, V.Hugh, Dempster, R, Walker, K, Perry, VH, Walker, Katharine, Anthony, D, Wells, Graham   +13 more
core   +1 more source

Expression of IP-10 Chemokine is Regulated by Pro-inflammatory Cytokines in Cultured Hepatocytes

Iranian Journal of Allergy, Asthma and Immunology, 2007
Chemokines are classified in four distinct groups as CXC, CC, CX3C and C, depending on the presence or absence of a motif called ELR (Arg-Leu-Glu) before the first cysteine residue in their structure. CXC chemokines are also subdivided into ELR+ and ELR-.
Gholamhossein Hassanshahi, Abdollah Jafarzadeh, Zohreh Ghorashi, Nazanin Zia Sheikholeslami, Alan James Dickson   +4 more
doaj  

Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer.

, 2017
Tumor-infiltrating T-cells are strongly associated with prognosis in colorectal cancer, but the mechanisms governing intratumoral lymphocyte recruitment are unclear.
Kistner, Larissa;Doll, Dietrich;Holtorf, Anne;Nitsche, Ulrich;Janssen, Klaus-Peter
core   +1 more source

Expression of CC and CXC chemokines and chemokine receptors in human leprosy skin lesions.

, 2003
We have investigated the expression of chemokines and their receptors in leprosy skin lesions using immunohistochemistry. Skin biopsies from 25 leprosy patients across the leprosy spectrum, 11 patients undergoing type I reversal reactions and four normal
D N J LOCKWOOD, Lockwood, DNJ, Musonda, AC, A A KIRKALDY, Kirkaldy, AA, S SUNEETHA, A C MUSONDA, Suneetha, S, S KHANOLKHAR-YOUNG, Khanolkhar-Young, S   +9 more
core   +1 more source

CXC chemokines located in the 4q21 region are up-regulated in breast cancer.

, 2007
International audienceRecent data suggest that chemokines could be essential players in breast carcinogenesis. We previously showed that the CXC chemokine CXCL8 (interleukin-8) was overexpressed in estrogen receptor alpha (ERalpha)-negative breast cell ...
Chavey, Carine, Vacher, Sophie, Busson, Muriel, Andrieu, Catherine, Bièche, Ivan, Le Corre, Ludovic, Guinebretière, Jean-Marc, Lidereau, Rosette, Lazennec, Gwendal, Burlinchon, Sandrine   +9 more
core   +1 more source