Results 181 to 190 of about 291,550 (218)

Biomarker-based clustering identifies distinct pulmonary function trajectories in early systemic sclerosis. [PDF]

Front Immunol
Uesugi-Uchida S, Asano Y, Endo H, Goto D, Jinnin M, Kawaguchi Y, Koike Y, Kuwana M, Tanaka S, Makino K, Matsushita T, Motegi SI, Sumida H, Ueda-Hayakawa I, Toyama T, Hasegawa M.   +15 more
europepmc   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

Cerebrospinal Fluid Cytokine and Chemokine Profiles in Autoimmune Encephalitis: A Cross-sectional Study. [PDF]

Ann Neurosci
Srivastava A, Singh RK, Banerjee J, A E, Das A, Ramanujam B, Parihar J, Pandit AK, V Y V, Vibha D, Chandra S, Srivastava MVP, Tripathi M.   +12 more
europepmc   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

Advanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen, Zhao‐Yu Liu, Gao‐Wen Qu, Run‐Hao Zeng, Wen‐Xia Yao, Yong‐Bing Zhou, Xue Liang, Yu‐Xiong Lai   +7 more
wiley   +1 more source

The Role of Rarely Studied Chemokines in Tumor Progression in Multiple Myeloma (MM). [PDF]

Cancers (Basel)
Korbecki J, Bosiacki M, Stelmach R, Barczak K.   +3 more
europepmc   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

Cytokine and chemokine networks in colorectal cancer. [PDF]

Front Immunol
Zhang X, Zhang Y, Wang R.
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

The function of chemokine-driven glial-neuronal interaction in chronic pain. [PDF]

Front Neurosci
Fan M, Liang Z, Shen J, Yang H, Zhao L, Li M, Zheng J.   +6 more
europepmc   +1 more source