Results 11 to 20 of about 291,550 (218)

The Roles of Stroma-Derived Chemokine in Different Stages of Cancer Metastases

open access: yesFrontiers in Immunology, 2020
The intricate interplay between malignant cells and host cellular and non-cellular components play crucial role in different stages of tumor development, progression, and metastases.
Shahid Hussain   +8 more
doaj   +1 more source

Chemokines and chemokine receptors: A new strategy for breast cancer therapy

open access: yesCancer Medicine, 2020
Chemokines and chemokine receptors not only participate in the development of tissue differentiation, hematopoiesis, inflammation, and immune regulation but also play an important role in the process of tumor development.
Hui Liu   +8 more
doaj   +1 more source

Targeting Chemokine—Glycosaminoglycan Interactions to Inhibit Inflammation

open access: yesFrontiers in Immunology, 2020
Leukocyte migration into tissues depends on the activity of chemokines that form concentration gradients to guide leukocytes to a specific site. Interaction of chemokines with their specific G protein-coupled receptors (GPCRs) on leukocytes induces ...
Helena Crijns   +2 more
doaj   +1 more source

Inflammatory Chemokines in Atherosclerosis

open access: yesCells, 2021
Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the formation of occlusive or rupture-prone lesions in large arteries. Complications of atherosclerosis can become severe and lead to cardiovascular diseases (CVD)
Selin Gencer   +4 more
doaj   +1 more source

Chemokines

open access: yesThe Scientific World Journal, 2007
Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion.
Richard Horuk
doaj   +1 more source

Chemokines in hyperthyroidism

open access: yesJournal of Clinical & Translational Endocrinology, 2019
The term “hyperthyroidism” indicates a condition due to an exaggerate production of thyroid hormone; the most frequent cause is Graves’ disease (GD).We review cytokines and chemokines in hyperthyroidism, with a special focus in GD.In GD, recruited Th1 ...
Silvia Martina Ferrari   +8 more
doaj   +1 more source

Chemokines in Gestational Diabetes Mellitus

open access: yesFrontiers in Immunology, 2022
BackgroundStudies investigating chemokines in gestational diabetes mellitus (GDM) have yielded mixed results. The purpose of this meta-analysis was to explore whether concentrations of chemokines in patients with GDM differed from that of the controls ...
Hongying Liu   +8 more
doaj   +1 more source

Chemokines Modulate Immune Surveillance in Tumorigenesis, Metastasis, and Response to Immunotherapy

open access: yesFrontiers in Immunology, 2019
Chemokines are small secreted proteins that orchestrate migration and positioning of immune cells within the tissues. Chemokines are essential for the function of the immune system.
Anna E. Vilgelm   +3 more
doaj   +1 more source

Duffy Antigen Receptor for Chemokines (DARC) and its Involvement in Patterning and Control of Inflammatory Chemokines

open access: yesFrontiers in Immunology, 2012
Leukocyte functions are linked to their migratory responses, which, in turn, are largely determined by the expression profile of classical chemokine receptors.
Igor eNovitzky-Basso, Antal eRot
doaj   +1 more source

Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization [PDF]

open access: yesOpen Biology, 2017
Chemokines control the migration of cells in normal physiological processes and in the context of disease such as inflammation, autoimmunity and cancer.
Douglas P. Dyer   +5 more
doaj   +1 more source

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