Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes [PDF]
Cytokines play an important role in ischemic injury and repair. However, little is known about their prognostic value in cardiovascular disease. The aim of this study was to investigate the prognostic importance of chemokines CCL3/MIP-1α, CCL5/RANTES and
van Dieijen-Visser, Marja P. +36 more
core +1 more source
The Roles of Stroma-Derived Chemokine in Different Stages of Cancer Metastases
The intricate interplay between malignant cells and host cellular and non-cellular components play crucial role in different stages of tumor development, progression, and metastases.
Shahid Hussain +8 more
doaj +1 more source
Chemokines and chemokine receptors: A new strategy for breast cancer therapy
Chemokines and chemokine receptors not only participate in the development of tissue differentiation, hematopoiesis, inflammation, and immune regulation but also play an important role in the process of tumor development.
Hui Liu +8 more
doaj +1 more source
Targeting Chemokine—Glycosaminoglycan Interactions to Inhibit Inflammation
Leukocyte migration into tissues depends on the activity of chemokines that form concentration gradients to guide leukocytes to a specific site. Interaction of chemokines with their specific G protein-coupled receptors (GPCRs) on leukocytes induces ...
Helena Crijns +2 more
doaj +1 more source
Chemokines are a group of cytokines involved in the mobilization of leukocytes, which play a role in host defense and a variety of pathological conditions, including cancer.
Ari Matsumoto +4 more
doaj +1 more source
Chemokine-induced secretion of gelatinase B in primary human monocytes [PDF]
Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited ...
Nelson, EL +17 more
core +1 more source
Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]
Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Hans-Joachim Anders +3 more
core +1 more source
Chemokines in Gestational Diabetes Mellitus
BackgroundStudies investigating chemokines in gestational diabetes mellitus (GDM) have yielded mixed results. The purpose of this meta-analysis was to explore whether concentrations of chemokines in patients with GDM differed from that of the controls ...
Hongying Liu +8 more
doaj +1 more source
Antimicrobial activities of chemokines: not just a side-effect? [PDF]
The large family of chemoattractant cytokines (chemokines) embraces multiple, in part unrelated functions that go well beyond chemotaxis. Undoubtedly, the control of immune cell migration (chemotaxis) is the single, unifying response mediated by all ...
Marlene eWolf +5 more
core +2 more sources
Chemokines Modulate Immune Surveillance in Tumorigenesis, Metastasis, and Response to Immunotherapy
Chemokines are small secreted proteins that orchestrate migration and positioning of immune cells within the tissues. Chemokines are essential for the function of the immune system.
Anna E. Vilgelm +3 more
doaj +1 more source

