Results 141 to 150 of about 25,830 (181)
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Critical Reviews in Oncology/Hematology, 1998
Detection of cancer at an early stage, by screening asymptomatic persons who are at risk for cancer has the aim of decreasing the number of cancer-related deaths. In practice, there are no guidelines for cancer screening in older people and it is often neglected, since reduced life expectancy and competing causes of death are considered to reduce the ...
L, Repetto +3 more
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Detection of cancer at an early stage, by screening asymptomatic persons who are at risk for cancer has the aim of decreasing the number of cancer-related deaths. In practice, there are no guidelines for cancer screening in older people and it is often neglected, since reduced life expectancy and competing causes of death are considered to reduce the ...
L, Repetto +3 more
openaire +2 more sources
Current Oncology Reports, 2004
The United States is experiencing a surge in the incidence of cutaneous malignant melanoma. Because melanoma is typically refractory to available anticancer therapy, exploration of preventive strategies has become a priority. In this review, the rationale for chemoprevention, a new and potentially powerful approach to controlling melanoma, is discussed.
Marie-France, Demierre, Glenn, Merlino
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The United States is experiencing a surge in the incidence of cutaneous malignant melanoma. Because melanoma is typically refractory to available anticancer therapy, exploration of preventive strategies has become a priority. In this review, the rationale for chemoprevention, a new and potentially powerful approach to controlling melanoma, is discussed.
Marie-France, Demierre, Glenn, Merlino
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Chemoprevention of breast cancer
Breast Cancer Research and Treatment, 1989The hypothesis that oestrogen is an important promoter of human breast cancer raises the possibility that endocrine intervention could prevent the disease. Various methods of reducing oestrogenic activity have been proposed including dietary control, progestin therapy, and ovarian ablation.
Powles, TJ +11 more
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Chemoprevention of Lung Cancer
Current Opinion in Pulmonary Medicine, 2004Lung cancer is one of the major causes of cancer-related deaths. Grim mortality figures argue powerfully for new approaches to control this disease. Chemoprevention is the use of specific natural or synthetic chemical agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer.
Victor, Cohen, Fadlo R, Khuri
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European Urology, 1999
Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and neck cancer and lung cancer ...
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Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and neck cancer and lung cancer ...
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Chemoprevention of breast cancer
The Lancet, 2000One in eight women in the United States will develop breast cancer. Family history, hormonal factors and benign breast disease have been identified as key factors in the development of breast cancer. Until recently the only treatment option for women identified as being at high risk of developing breast cancer was bilateral prophylactic mastectomy ...
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Chemoprevention of Prostate Cancer
Annual Review of Medicine, 2005Prostate cancer is an attractive target for chemoprevention because of its ubiquity, treatment-related morbidity, long latency between premalignant lesions and clinically evident cancer, and defined molecular pathogenesis. The Prostate Cancer Prevention Trial has provided the first firm evidence that this cancer can be prevented by a relatively ...
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Preclinical Development of Chemopreventive Agents for Chemoprevention
2017Chemopreventive agents regulate cellular and molecular events by modulation of phase I and phase II metabolizing enzymes inducing DNA repair and inhibiting growth and cell cycle progression and differentiation and apoptosis, growth hormonal activity modulation, ligands for nuclear receptors, and alteration of chromatin structure.
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Chemoprevention of prostate cancer
Cancer and Metastasis Reviews, 2002Chemoprevention is prevention of cancer by administering natural or synthetic chemicals. Anti-androgens are among the promising chemopreventive agents for prostate cancer because prostate epithelium is androgen dependent. A National Cancer Institute supported large, randomized, clinical prostate cancer chemoprevention trial has been conducted to test ...
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Role of Phytochemicals in Cancer Chemoprevention: Insights
Antioxidants, 2021Heidi Abrahamse +2 more
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